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Page 1
Burosumab vs conventional therapy in children with X-linked hypophosphatemia: results of the open-label, phase 3 extension period.
Ward LM, Högler W, Glorieux FH, Portale AA, Whyte MP, Munns CF, Nilsson O, Simmons JH, Padidela R, Namba N, Cheong HI, Sochett E, Muroya K, Tanaka H, Pitukcheewanont P, Gottesman GS, Biggin A, Perwad F, Chen A, Lawrence Merritt Ii J, Imel EA. Ward LM, et al. Among authors: padidela r. JBMR Plus. 2024 Jan 4;8(1):ziad001. doi: 10.1093/jbmrpl/ziad001. eCollection 2024 Jan. JBMR Plus. 2024. PMID: 38690124 Free PMC article. Clinical Trial.
Burosumab Therapy in Children with X-Linked Hypophosphatemia.
Carpenter TO, Whyte MP, Imel EA, Boot AM, Högler W, Linglart A, Padidela R, Van't Hoff W, Mao M, Chen CY, Skrinar A, Kakkis E, San Martin J, Portale AA. Carpenter TO, et al. Among authors: padidela r. N Engl J Med. 2018 May 24;378(21):1987-1998. doi: 10.1056/NEJMoa1714641. N Engl J Med. 2018. PMID: 29791829 Free article. Clinical Trial.
Paradoxical Response of Parathyroid Hormone to Vitamin D-Calcium Supplementation in Indian Children.
Mandlik RM, Mughal ZM, Khadilkar AV, Ekbote VH, Kajale NA, Patwardhan VG, Khadilkar VV, Padidela R. Mandlik RM, et al. Among authors: padidela r. J Pediatr. 2020 Jan;216:197-203. doi: 10.1016/j.jpeds.2019.09.028. Epub 2019 Nov 6. J Pediatr. 2020. PMID: 31704050 Clinical Trial.

After supplementation, vitamin D group, compared with the non-vitamin D group, had significantly (P < .05) greater 25(OH)D (83.9 30.1 nmol/L vs 58.3 15.7 nmol/L), significantly greater PTH (6.7 3.6 pmol/L vs 5.5 3.2 pmol/L), and positive correlation (r(s) = 0.24) betwee

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After supplementation, vitamin D group, compared with the non-vitamin D group, had significantly (P < .05) greater 25(OH)D (83.9 30.1 nmo

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Muscle and bone parameters in underprivileged Indian children and adolescents with T1DM.
Dongare-Bhor S, Lohiya N, Maheshwari A, Ekbote V, Chiplonkar S, Padidela R, Mughal Z, Khadilkar V, Khadilkar A. Dongare-Bhor S, et al. Among authors: padidela r. Bone. 2020 Jan;130:115074. doi: 10.1016/j.bone.2019.115074. Epub 2019 Oct 15. Bone. 2020. PMID: 31626994
Trabecular density and HbA1C concentrations were negatively correlated (R = -0.18, p < 0.05) as was muscle area and HbA1C concentrations (R = -0.17, p < 0.05,). ...

Trabecular density and HbA1C concentrations were negatively correlated (R = -0.18, p < 0.05) as was muscle area and HbA1C concentr

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Comprehensive Screening of Eight Known Causative Genes in Congenital Hypothyroidism With Gland-in-Situ.
Nicholas AK, Serra EG, Cangul H, Alyaarubi S, Ullah I, Schoenmakers E, Deeb A, Habeb AM, Almaghamsi M, Peters C, Nathwani N, Aycan Z, Saglam H, Bober E, Dattani M, Shenoy S, Murray PG, Babiker A, Willemsen R, Thankamony A, Lyons G, Irwin R, Padidela R, Tharian K, Davies JH, Puthi V, Park SM, Massoud AF, Gregory JW, Albanese A, Pease-Gevers E, Martin H, Brugger K, Maher ER, Chatterjee VK, Anderson CA, Schoenmakers N. Nicholas AK, et al. Among authors: padidela r. J Clin Endocrinol Metab. 2016 Dec;101(12):4521-4531. doi: 10.1210/jc.2016-1879. Epub 2016 Aug 15. J Clin Endocrinol Metab. 2016. PMID: 27525530 Free PMC article.
Feeding Problems Are Persistent in Children with Severe Congenital Hyperinsulinism.
Banerjee I, Forsythe L, Skae M, Avatapalle HB, Rigby L, Bowden LE, Craigie R, Padidela R, Ehtisham S, Patel L, Cosgrove KE, Dunne MJ, Clayton PE. Banerjee I, et al. Among authors: padidela r. Front Endocrinol (Lausanne). 2016 Feb 9;7:8. doi: 10.3389/fendo.2016.00008. eCollection 2016. Front Endocrinol (Lausanne). 2016. PMID: 26903946 Free PMC article.
Those undergoing focal lesionectomy also had reduced FPs at 6 months after diagnosis [OR (95% CI) 0.01 (0.0-0.2), R (2) = 0.42, p = 0.004]. These observations suggest that persistence of hyperinsulinism was associated with FPs. ...
Those undergoing focal lesionectomy also had reduced FPs at 6 months after diagnosis [OR (95% CI) 0.01 (0.0-0.2), R (2) = 0.42, p = 0 …
Monitoring response to conventional treatment in children with XLH: Value of ALP and Rickets Severity Score (RSS) in a real world setting.
Uday S, Shaw NJ, Mughal MZ, Randell T, Högler W, Santos R, Padidela R. Uday S, et al. Among authors: padidela r. Bone. 2021 Oct;151:116025. doi: 10.1016/j.bone.2021.116025. Epub 2021 May 28. Bone. 2021. PMID: 34052463
There was no statistically significant (p > 0.05) correlation between ALP z scores and knee (r = 0.07) or total (r = 0.12) RSS. CONCLUSIONS: Conventional therapy was not effective in significantly improving biochemical and radiological features of disease. ...
There was no statistically significant (p > 0.05) correlation between ALP z scores and knee (r = 0.07) or total (r = 0.12) …
Vineland adaptive behavior scales to identify neurodevelopmental problems in children with Congenital Hyperinsulinism (CHI).
Salomon-Estebanez M, Mohamed Z, Michaelidou M, Collins H, Rigby L, Skae M, Padidela R, Rust S, Dunne M, Cosgrove K, Banerjee I, Nicholson J. Salomon-Estebanez M, et al. Among authors: padidela r. Orphanet J Rare Dis. 2017 May 22;12(1):96. doi: 10.1186/s13023-017-0648-7. Orphanet J Rare Dis. 2017. PMID: 28532504 Free PMC article.

VABS-II Total scores correctly identified developmental delay diagnosed by objective assessment in the majority [odds ratio (OR) (95% confidence intervals, CI) 0.52 (0.38, 0.73), p < 0.001] with 95% specificity [area under curve (CI) 0.80 (0.68, 0.90), p < 0.001] for cut-of

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VABS-II Total scores correctly identified developmental delay diagnosed by objective assessment in the majority [odds ratio (OR) (95% confid …
Impact of dietary nutrient intake and physical activity on body composition and growth in Indian children.
Khadilkar AV, Chiplonkar SA, Kajale NA, Ekbote VH, Parathasarathi L, Padidela R, Khadilkar VV. Khadilkar AV, et al. Among authors: padidela r. Pediatr Res. 2018 Apr;83(4):843-850. doi: 10.1038/pr.2017.322. Epub 2018 Jan 17. Pediatr Res. 2018. PMID: 29278646
HAZ was negatively associated with inactivity (beta=-0.0001, P=0.049) in boys and girls (R(2)=0.104, P<0.01). Further, body fat percentage was negatively correlated with moderate or light activity and antioxidant intakes (P<0.01) but not with dietary fat intake. ...
HAZ was negatively associated with inactivity (beta=-0.0001, P=0.049) in boys and girls (R(2)=0.104, P<0.01). Further, body fat pe …
Duration of Casual Sunlight Exposure Necessary for Adequate Vitamin D Status in Indian Men.
Patwardhan VG, Mughal ZM, Chiplonkar SA, Webb AR, Kift R, Khadilkar VV, Padidela R, Khadilkar AV. Patwardhan VG, et al. Among authors: padidela r. Indian J Endocrinol Metab. 2018 Mar-Apr;22(2):249-255. doi: 10.4103/ijem.IJEM_473_17. Indian J Endocrinol Metab. 2018. PMID: 29911040 Free PMC article.

A hyperbolic function for the relationship between PSU measured sunlight exposure in standard erythema dose (SED) and serum 25(OH)D concentrations (r = 0.87, P < 0.01) revealed that daily exposure of 1 SED was sufficient to maintain serum 25(OH)D concentrations over 50

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A hyperbolic function for the relationship between PSU measured sunlight exposure in standard erythema dose (SED) and serum 25(OH)D concentr …
14 results