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Year Number of Results
1964 1
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2009 2
2010 2
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70 results

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Page 1
Rational discovery of molecular glue degraders via scalable chemical profiling.
Mayor-Ruiz C, Bauer S, Brand M, Kozicka Z, Siklos M, Imrichova H, Kaltheuner IH, Hahn E, Seiler K, Koren A, Petzold G, Fellner M, Bock C, Müller AC, Zuber J, Geyer M, Thomä NH, Kubicek S, Winter GE. Mayor-Ruiz C, et al. Nat Chem Biol. 2020 Nov;16(11):1199-1207. doi: 10.1038/s41589-020-0594-x. Epub 2020 Aug 3. Nat Chem Biol. 2020. PMID: 32747809 Free PMC article.
Target 2035 - update on the quest for a probe for every protein.
Müller S, Ackloo S, Al Chawaf A, Al-Lazikani B, Antolin A, Baell JB, Beck H, Beedie S, Betz UAK, Bezerra GA, Brennan PE, Brown D, Brown PJ, Bullock AN, Carter AJ, Chaikuad A, Chaineau M, Ciulli A, Collins I, Dreher J, Drewry D, Edfeldt K, Edwards AM, Egner U, Frye SV, Fuchs SM, Hall MD, Hartung IV, Hillisch A, Hitchcock SH, Homan E, Kannan N, Kiefer JR, Knapp S, Kostic M, Kubicek S, Leach AR, Lindemann S, Marsden BD, Matsui H, Meier JL, Merk D, Michel M, Morgan MR, Mueller-Fahrnow A, Owen DR, Perry BG, Rosenberg SH, Saikatendu KS, Schapira M, Scholten C, Sharma S, Simeonov A, Sundström M, Superti-Furga G, Todd MH, Tredup C, Vedadi M, von Delft F, Willson TM, Winter GE, Workman P, Arrowsmith CH. Müller S, et al. RSC Med Chem. 2021 Dec 3;13(1):13-21. doi: 10.1039/d1md00228g. eCollection 2022 Jan 27. RSC Med Chem. 2021. PMID: 35211674 Free PMC article.
Pooled multicolour tagging for visualizing subcellular protein dynamics.
Reicher A, Reiniš J, Ciobanu M, Růžička P, Malik M, Siklos M, Kartysh V, Tomek T, Koren A, Rendeiro AF, Kubicek S. Reicher A, et al. Nat Cell Biol. 2024 May;26(5):745-756. doi: 10.1038/s41556-024-01407-w. Epub 2024 Apr 19. Nat Cell Biol. 2024. PMID: 38641660 Free PMC article.
N-substituted 5-amino-6-methylpyrazine-2,3-dicarbonitriles: microwave-assisted synthesis and biological properties.
Jandourek O, Dolezal M, Paterova P, Kubicek V, Pesko M, Kunes J, Coffey A, Guo J, Kralova K. Jandourek O, et al. Molecules. 2014 Jan 7;19(1):651-71. doi: 10.3390/molecules19010651. Molecules. 2014. PMID: 24402198 Free PMC article.
The compounds were evaluated for their antibacterial, antifungal and herbicidal activity. Compounds 3 (R=3,4-Cl), 9 (R=2-Cl) and 11 (R=4-CF3) showed good antimycobacterial activity against Mycobacterium tuberculosis (MIC=6.25 g/mL). ...The presented compound …
The compounds were evaluated for their antibacterial, antifungal and herbicidal activity. Compounds 3 (R=3,4-Cl), 9 (R=2-Cl) a …
Indirect (implicit) and direct (explicit) self-esteem measures are virtually unrelated: A meta-analysis of the initial preference task.
Pietschnig J, Gittler G, Stieger S, Forster M, Gadek N, Gartus A, Kocsis-Bogar K, Kubicek B, Lüftenegger M, Olsen J, Prem R, Ruiz N, Serfas BG, Voracek M. Pietschnig J, et al. PLoS One. 2018 Sep 6;13(9):e0202873. doi: 10.1371/journal.pone.0202873. eCollection 2018. PLoS One. 2018. PMID: 30188907 Free PMC article.
RESULTS: There was no noteworthy correlation between IPT-based implicit and explicit self-esteem (r = .102), indicating conceptual independence of these two constructs. Effects were stronger when the B-algorithm was used for calculation of IPT-scores and the IPT was admini …
RESULTS: There was no noteworthy correlation between IPT-based implicit and explicit self-esteem (r = .102), indicating conceptual in …
Methylene-bis[(aminomethyl)phosphinic acids]: synthesis, acid-base and coordination properties.
David T, Procházková S, Havlíčková J, Kotek J, Kubíček V, Hermann P, Lukeš I. David T, et al. Dalton Trans. 2013 Feb 21;42(7):2414-22. doi: 10.1039/c2dt32045b. Epub 2012 Dec 4. Dalton Trans. 2013. PMID: 23208292
Three symmetrical methylene-bis[(aminomethyl)phosphinic acids] bearing different substituents on the central carbon atom, (NH(2)CH(2))PO(2)H-C(R(1))(R(2))-PO(2)H(CH(2)NH(2)) where R(1) = OH, R(2) = Me (H(2)L(1)), R(1) = OH, R(2) = Ph (H(2 …
Three symmetrical methylene-bis[(aminomethyl)phosphinic acids] bearing different substituents on the central carbon atom, (NH(2)CH(2))PO(2)H …
Biological variation of proprotein convertase subtilisin/kexin type 9 (PCSK9) in human serum.
Jabor A, Vacková T, Kubíček Z, Komrsková J, Protuš M, Franeková J. Jabor A, et al. Clin Chim Acta. 2021 Oct;521:59-63. doi: 10.1016/j.cca.2021.06.023. Epub 2021 Jun 18. Clin Chim Acta. 2021. PMID: 34153278
Serum concentration of PCSK9 was measured by a Quantikine ELISA assay (R&D systems, Bio-Techne Ltd., UK) on a DS2 ELISA reader (Dynex Technologies GmbH, Germany). ...
Serum concentration of PCSK9 was measured by a Quantikine ELISA assay (R&D systems, Bio-Techne Ltd., UK) on a DS2 ELISA reader (D …
70 results