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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 1
2002 1
2003 4
2004 4
2005 1
2006 3
2007 4
2008 8
2009 3
2020 0
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27 results
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Page 1
A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling.
Knight ZA, Gonzalez B, Feldman ME, Zunder ER, Goldenberg DD, Williams O, Loewith R, Stokoe D, Balla A, Toth B, Balla T, Weiss WA, Williams RL, Shokat KM. Knight ZA, et al. Cell. 2006 May 19;125(4):733-47. doi: 10.1016/j.cell.2006.03.035. Epub 2006 Apr 27. Cell. 2006. PMID: 16647110 Free PMC article.
Regulation of meiotic recombination via Mek1-mediated Rad54 phosphorylation.
Niu H, Wan L, Busygina V, Kwon Y, Allen JA, Li X, Kunz RC, Kubota K, Wang B, Sung P, Shokat KM, Gygi SP, Hollingsworth NM. Niu H, et al. Mol Cell. 2009 Nov 13;36(3):393-404. doi: 10.1016/j.molcel.2009.09.029. Mol Cell. 2009. PMID: 19917248 Free PMC article.
Selective kinase inhibition by exploiting differential pathway sensitivity.
Kung C, Kenski DM, Krukenberg K, Madhani HD, Shokat KM. Kung C, et al. Chem Biol. 2006 Apr;13(4):399-407. doi: 10.1016/j.chembiol.2006.02.004. Chem Biol. 2006. PMID: 16632252 Free PMC article.
Tuning the activation threshold of a kinase network by nested feedback loops.
Justman QA, Serber Z, Ferrell JE Jr, El-Samad H, Shokat KM. Justman QA, et al. Science. 2009 Apr 24;324(5926):509-12. doi: 10.1126/science.1169498. Science. 2009. PMID: 19390045 Free PMC article.
Chemical genetic analysis of Apg1 reveals a non-kinase role in the induction of autophagy.
Abeliovich H, Zhang C, Dunn WA Jr, Shokat KM, Klionsky DJ. Abeliovich H, et al. Mol Biol Cell. 2003 Feb;14(2):477-90. doi: 10.1091/mbc.e02-07-0413. Mol Biol Cell. 2003. PMID: 12589048 Free PMC article.
Chemical genomic profiling to identify intracellular targets of a multiplex kinase inhibitor.
Kung C, Kenski DM, Dickerson SH, Howson RW, Kuyper LF, Madhani HD, Shokat KM. Kung C, et al. Proc Natl Acad Sci U S A. 2005 Mar 8;102(10):3587-92. doi: 10.1073/pnas.0407170102. Epub 2005 Feb 28. Proc Natl Acad Sci U S A. 2005. PMID: 15738404 Free PMC article.
Two cyclin-dependent kinases promote RNA polymerase II transcription and formation of the scaffold complex.
Liu Y, Kung C, Fishburn J, Ansari AZ, Shokat KM, Hahn S. Liu Y, et al. Mol Cell Biol. 2004 Feb;24(4):1721-35. doi: 10.1128/mcb.24.4.1721-1735.2004. Mol Cell Biol. 2004. PMID: 14749387 Free PMC article.
Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases.
Apsel B, Blair JA, Gonzalez B, Nazif TM, Feldman ME, Aizenstein B, Hoffman R, Williams RL, Shokat KM, Knight ZA. Apsel B, et al. Nat Chem Biol. 2008 Nov;4(11):691-9. doi: 10.1038/nchembio.117. Epub 2008 Oct 12. Nat Chem Biol. 2008. PMID: 18849971 Free PMC article.
Structure and substrate recruitment of the human spindle checkpoint kinase Bub1.
Kang J, Yang M, Li B, Qi W, Zhang C, Shokat KM, Tomchick DR, Machius M, Yu H. Kang J, et al. Mol Cell. 2008 Nov 7;32(3):394-405. doi: 10.1016/j.molcel.2008.09.017. Mol Cell. 2008. PMID: 18995837 Free PMC article.
A coupled chemical-genetic and bioinformatic approach to Polo-like kinase pathway exploration.
Snead JL, Sullivan M, Lowery DM, Cohen MS, Zhang C, Randle DH, Taunton J, Yaffe MB, Morgan DO, Shokat KM. Snead JL, et al. Chem Biol. 2007 Nov;14(11):1261-72. doi: 10.1016/j.chembiol.2007.09.011. Chem Biol. 2007. PMID: 18022565 Free PMC article.
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