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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1990 1
1991 2
2009 5
2010 4
2011 6
2012 8
2013 2
2014 5
2015 11
2016 2
2017 5
2018 3
2019 2
2020 1
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53 results
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Page 1
Targeting metabolism to regulate immune responses in autoimmunity and cancer.
Patel CH, Leone RD, Horton MR, Powell JD. Patel CH, et al. Nat Rev Drug Discov. 2019 Sep;18(9):669-688. doi: 10.1038/s41573-019-0032-5. Epub 2019 Jul 30. Nat Rev Drug Discov. 2019. PMID: 31363227 Review.
Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR.
Walton ZE, Patel CH, Brooks RC, Yu Y, Ibrahim-Hashim A, Riddle M, Porcu A, Jiang T, Ecker BL, Tameire F, Koumenis C, Weeraratna AT, Welsh DK, Gillies R, Alwine JC, Zhang L, Powell JD, Dang CV. Walton ZE, et al. Cell. 2018 Jun 28;174(1):72-87.e32. doi: 10.1016/j.cell.2018.05.009. Epub 2018 May 31. Cell. 2018. PMID: 29861175 Free PMC article.
Murine Full-thickness Skin Transplantation.
Cheng CH, Lee CF, Fryer M, Furtmüller GJ, Oh B, Powell JD, Brandacher G. Cheng CH, et al. J Vis Exp. 2017 Jan 2;(119):55105. doi: 10.3791/55105. J Vis Exp. 2017. PMID: 28117792 Free PMC article.
PKG1-modified TSC2 regulates mTORC1 activity to counter adverse cardiac stress.
Ranek MJ, Kokkonen-Simon KM, Chen A, Dunkerly-Eyring BL, Vera MP, Oeing CU, Patel CH, Nakamura T, Zhu G, Bedja D, Sasaki M, Holewinski RJ, Van Eyk JE, Powell JD, Lee DI, Kass DA. Ranek MJ, et al. Nature. 2019 Feb;566(7743):264-269. doi: 10.1038/s41586-019-0895-y. Epub 2019 Jan 30. Nature. 2019. PMID: 30700906 Free PMC article.
Targeting T cell metabolism to regulate T cell activation, differentiation and function in disease.
Patel CH, Powell JD. Patel CH, et al. Curr Opin Immunol. 2017 Jun;46:82-88. doi: 10.1016/j.coi.2017.04.006. Epub 2017 May 15. Curr Opin Immunol. 2017. PMID: 28521236 Free PMC article. Review.
Developing a pro-regenerative biomaterial scaffold microenvironment requires T helper 2 cells.
Sadtler K, Estrellas K, Allen BW, Wolf MT, Fan H, Tam AJ, Patel CH, Luber BS, Wang H, Wagner KR, Powell JD, Housseau F, Pardoll DM, Elisseeff JH. Sadtler K, et al. Science. 2016 Apr 15;352(6283):366-70. doi: 10.1126/science.aad9272. Science. 2016. PMID: 27081073 Free PMC article.
mTORC1 and mTORC2 selectively regulate CD8⁺ T cell differentiation.
Pollizzi KN, Patel CH, Sun IH, Oh MH, Waickman AT, Wen J, Delgoffe GM, Powell JD. Pollizzi KN, et al. J Clin Invest. 2015 May;125(5):2090-108. doi: 10.1172/JCI77746. Epub 2015 Apr 20. J Clin Invest. 2015. PMID: 25893604 Free PMC article.
Regulation of immune responses by mTOR.
Powell JD, Pollizzi KN, Heikamp EB, Horton MR. Powell JD, et al. Annu Rev Immunol. 2012;30:39-68. doi: 10.1146/annurev-immunol-020711-075024. Epub 2011 Nov 29. Annu Rev Immunol. 2012. PMID: 22136167 Free PMC article. Review.
A2aR antagonists: Next generation checkpoint blockade for cancer immunotherapy.
Leone RD, Lo YC, Powell JD. Leone RD, et al. Comput Struct Biotechnol J. 2015 Apr 8;13:265-72. doi: 10.1016/j.csbj.2015.03.008. eCollection 2015. Comput Struct Biotechnol J. 2015. PMID: 25941561 Free PMC article. Review.
Targeting Metabolism as a Novel Therapeutic Approach to Autoimmunity, Inflammation, and Transplantation.
Bettencourt IA, Powell JD. Bettencourt IA, et al. J Immunol. 2017 Feb 1;198(3):999-1005. doi: 10.4049/jimmunol.1601318. J Immunol. 2017. PMID: 28115589 Free PMC article. Review.
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