R01 CA030002/CA/NCI NIH HHS/United States[Grant Number] - Search Results

Year	Number of Results
2000	1
2001	1
2003	1
2004	1
2005	1
2006	1
2007	3
2008	3
2009	4
2011	3
2012	4
2013	1
2014	4
2015	1
2016	3
2022	0

1

Targeting the phosphoinositide 3-kinase pathway in cancer.

Liu P, Cheng H, Roberts TM, Zhao JJ. Liu P, et al. Nat Rev Drug Discov. 2009 Aug;8(8):627-44. doi: 10.1038/nrd2926. Nat Rev Drug Discov. 2009. PMID: 19644473 Free PMC article. Review.

2

Should individual PI3 kinase isoforms be targeted in cancer?

Jia S, Roberts TM, Zhao JJ. Jia S, et al. Curr Opin Cell Biol. 2009 Apr;21(2):199-208. doi: 10.1016/j.ceb.2008.12.007. Epub 2009 Feb 4. Curr Opin Cell Biol. 2009. PMID: 19200708 Free PMC article. Review.

3

Lessons from polyoma middle T antigen on signaling and transformation: A DNA tumor virus contribution to the war on cancer.

Schaffhausen BS, Roberts TM. Schaffhausen BS, et al. Virology. 2009 Feb 20;384(2):304-16. doi: 10.1016/j.virol.2008.09.042. Epub 2008 Nov 20. Virology. 2009. PMID: 19022468 Free PMC article. Review.

4

Polyoma small T antigen triggers cell death via mitotic catastrophe.

Pores Fernando AT, Andrabi S, Cizmecioglu O, Zhu C, Livingston DM, Higgins JM, Schaffhausen BS, Roberts TM. Pores Fernando AT, et al. Oncogene. 2015 May 7;34(19):2483-92. doi: 10.1038/onc.2014.192. Epub 2014 Jul 7. Oncogene. 2015. PMID: 24998850 Free PMC article.

5

Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations.

Pugh TJ, Weeraratne SD, Archer TC, Pomeranz Krummel DA, Auclair D, Bochicchio J, Carneiro MO, Carter SL, Cibulskis K, Erlich RL, Greulich H, Lawrence MS, Lennon NJ, McKenna A, Meldrim J, Ramos AH, Ross MG, Russ C, Shefler E, Sivachenko A, Sogoloff B, Stojanov P, Tamayo P, Mesirov JP, Amani V, Teider N, Sengupta S, Francois JP, Northcott PA, Taylor MD, Yu F, Crabtree GR, Kautzman AG, Gabriel SB, Getz G, Jäger N, Jones DT, Lichter P, Pfister SM, Roberts TM, Meyerson M, Pomeroy SL, Cho YJ. Pugh TJ, et al. Nature. 2012 Aug 2;488(7409):106-10. doi: 10.1038/nature11329. Nature. 2012. PMID: 22820256 Free PMC article.

6

Rac1-mediated membrane raft localization of PI3K/p110β is required for its activation by GPCRs or PTEN loss.

Cizmecioglu O, Ni J, Xie S, Zhao JJ, Roberts TM. Cizmecioglu O, et al. Elife. 2016 Oct 4;5:e17635. doi: 10.7554/eLife.17635. Elife. 2016. PMID: 27700986 Free PMC article.

7

Functional characterization of an isoform-selective inhibitor of PI3K-p110β as a potential anticancer agent.

Ni J, Liu Q, Xie S, Carlson C, Von T, Vogel K, Riddle S, Benes C, Eck M, Roberts T, Gray N, Zhao J. Ni J, et al. Cancer Discov. 2012 May;2(5):425-33. doi: 10.1158/2159-8290.CD-12-0003. Epub 2012 Apr 12. Cancer Discov. 2012. PMID: 22588880 Free PMC article.

8

Opposing effects of androgen deprivation and targeted therapy on prostate cancer prevention.

Jia S, Gao X, Lee SH, Maira SM, Wu X, Stack EC, Signoretti S, Loda M, Zhao JJ, Roberts TM. Jia S, et al. Cancer Discov. 2013 Jan;3(1):44-51. doi: 10.1158/2159-8290.CD-12-0262. Epub 2012 Dec 20. Cancer Discov. 2013. PMID: 23258246 Free PMC article.

9

PI3K isoform dependence of PTEN-deficient tumors can be altered by the genetic context.

Schmit F, Utermark T, Zhang S, Wang Q, Von T, Roberts TM, Zhao JJ. Schmit F, et al. Proc Natl Acad Sci U S A. 2014 Apr 29;111(17):6395-400. doi: 10.1073/pnas.1323004111. Epub 2014 Apr 15. Proc Natl Acad Sci U S A. 2014. PMID: 24737887 Free PMC article.

10

The p110α and p110β isoforms of PI3K play divergent roles in mammary gland development and tumorigenesis.

Utermark T, Rao T, Cheng H, Wang Q, Lee SH, Wang ZC, Iglehart JD, Roberts TM, Muller WJ, Zhao JJ. Utermark T, et al. Genes Dev. 2012 Jul 15;26(14):1573-86. doi: 10.1101/gad.191973.112. Genes Dev. 2012. PMID: 22802530 Free PMC article.

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