R01 CA068490/CA/NCI NIH HHS/United States[Grant Number] - Search Results

Year	Number of Results
2000	1
2007	1
2009	1
2010	6
2011	8
2012	4
2013	8
2014	6
2015	1
2016	2
2017	1
2019	1
2020	2
2021	1
2024	0

1

The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins.

Lu G, Middleton RE, Sun H, Naniong M, Ott CJ, Mitsiades CS, Wong KK, Bradner JE, Kaelin WG Jr. Lu G, et al. Science. 2014 Jan 17;343(6168):305-9. doi: 10.1126/science.1244917. Epub 2013 Nov 29. Science. 2014. PMID: 24292623 Free PMC article.

2

Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate.

Chakraborty AA, Laukka T, Myllykoski M, Ringel AE, Booker MA, Tolstorukov MY, Meng YJ, Meier SR, Jennings RB, Creech AL, Herbert ZT, McBrayer SK, Olenchock BA, Jaffe JD, Haigis MC, Beroukhim R, Signoretti S, Koivunen P, Kaelin WG Jr. Chakraborty AA, et al. Science. 2019 Mar 15;363(6432):1217-1222. doi: 10.1126/science.aaw1026. Epub 2019 Mar 14. Science. 2019. PMID: 30872525 Free PMC article.

3

Comprehensive molecular characterization of clear cell renal cell carcinoma.

Cancer Genome Atlas Research Network. Cancer Genome Atlas Research Network. Nature. 2013 Jul 4;499(7456):43-9. doi: 10.1038/nature12222. Epub 2013 Jun 23. Nature. 2013. PMID: 23792563 Free PMC article.

4

Skp2 dictates cell cycle-dependent metabolic oscillation between glycolysis and TCA cycle.

Liu J, Peng Y, Shi L, Wan L, Inuzuka H, Long J, Guo J, Zhang J, Yuan M, Zhang S, Wang X, Gao J, Dai X, Furumoto S, Jia L, Pandolfi PP, Asara JM, Kaelin WG Jr, Liu J, Wei W. Liu J, et al. Cell Res. 2021 Jan;31(1):80-93. doi: 10.1038/s41422-020-0372-z. Epub 2020 Jul 15. Cell Res. 2021. PMID: 32669607 Free PMC article.

5

Influence of metabolism on epigenetics and disease.

Kaelin WG Jr, McKnight SL. Kaelin WG Jr, et al. Cell. 2013 Mar 28;153(1):56-69. doi: 10.1016/j.cell.2013.03.004. Cell. 2013. PMID: 23540690 Free PMC article. Review.

6

Genome-wide Screening Identifies SFMBT1 as an Oncogenic Driver in Cancer with VHL Loss.

Liu X, Simon JM, Xie H, Hu L, Wang J, Zurlo G, Fan C, Ptacek TS, Herring L, Tan X, Li M, Baldwin AS, Kim WY, Wu T, Kirschner MW, Gong K, Zhang Q. Liu X, et al. Mol Cell. 2020 Mar 19;77(6):1294-1306.e5. doi: 10.1016/j.molcel.2020.01.009. Epub 2020 Feb 4. Mol Cell. 2020. PMID: 32023483 Free PMC article.

7

The VHL/HIF axis in clear cell renal carcinoma.

Shen C, Kaelin WG Jr. Shen C, et al. Semin Cancer Biol. 2013 Feb;23(1):18-25. doi: 10.1016/j.semcancer.2012.06.001. Epub 2012 Jun 13. Semin Cancer Biol. 2013. PMID: 22705278 Free PMC article. Review.

8

What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer.

Losman JA, Kaelin WG Jr. Losman JA, et al. Genes Dev. 2013 Apr 15;27(8):836-52. doi: 10.1101/gad.217406.113. Genes Dev. 2013. PMID: 23630074 Free PMC article. Review.

9

New insights into the biology of renal cell carcinoma.

Li L, Kaelin WG Jr. Li L, et al. Hematol Oncol Clin North Am. 2011 Aug;25(4):667-86. doi: 10.1016/j.hoc.2011.04.004. Hematol Oncol Clin North Am. 2011. PMID: 21763962 Free PMC article. Review.

10

Cancer and altered metabolism: potential importance of hypoxia-inducible factor and 2-oxoglutarate-dependent dioxygenases.

Kaelin WG Jr. Kaelin WG Jr. Cold Spring Harb Symp Quant Biol. 2011;76:335-45. doi: 10.1101/sqb.2011.76.010975. Epub 2011 Nov 16. Cold Spring Harb Symp Quant Biol. 2011. PMID: 22089927 Free PMC article. Review.

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