R01 CA090787/CA/NCI NIH HHS/United States[Grant Number] - Search Results

Year	Number of Results
2006	1
2007	1
2008	1
2009	1
2010	4
2011	3
2012	2
2014	2
2015	3
2016	1
2024	0

1

Potent cytotoxic arylnaphthalene lignan lactones from Phyllanthus poilanei.

Ren Y, Lantvit DD, Deng Y, Kanagasabai R, Gallucci JC, Ninh TN, Chai HB, Soejarto DD, Fuchs JR, Yalowich JC, Yu J, Swanson SM, Kinghorn AD. Ren Y, et al. J Nat Prod. 2014 Jun 27;77(6):1494-504. doi: 10.1021/np5002785. Epub 2014 Jun 12. J Nat Prod. 2014. PMID: 24937209 Free PMC article.

2

Cytotoxic and natural killer cell stimulatory constituents of Phyllanthus songboiensis.

Ren Y, Yuan C, Deng Y, Kanagasabai R, Ninh TN, Tu VT, Chai HB, Soejarto DD, Fuchs JR, Yalowich JC, Yu J, Kinghorn AD. Ren Y, et al. Phytochemistry. 2015 Mar;111:132-40. doi: 10.1016/j.phytochem.2014.12.014. Epub 2015 Jan 14. Phytochemistry. 2015. PMID: 25596805 Free PMC article.

3

Mechanism of the cytotoxicity of the diazoparaquinone antitumor antibiotic kinamycin F.

O'Hara KA, Wu X, Patel D, Liang H, Yalowich JC, Chen N, Goodfellow V, Adedayo O, Dmitrienko GI, Hasinoff BB. O'Hara KA, et al. Free Radic Biol Med. 2007 Oct 15;43(8):1132-44. doi: 10.1016/j.freeradbiomed.2007.07.005. Epub 2007 Jul 13. Free Radic Biol Med. 2007. PMID: 17854709 Free PMC article.

4

Cadmium is a catalytic inhibitor of DNA topoisomerase II.

Wu X, Yalowich JC, Hasinoff BB. Wu X, et al. J Inorg Biochem. 2011 Jun;105(6):833-8. doi: 10.1016/j.jinorgbio.2011.02.007. Epub 2011 Feb 26. J Inorg Biochem. 2011. PMID: 21497582 Free PMC article.

5

Myeloperoxidase-catalyzed metabolism of etoposide to its quinone and glutathione adduct forms in HL60 cells.

Fan Y, Schreiber EM, Giorgianni A, Yalowich JC, Day BW. Fan Y, et al. Chem Res Toxicol. 2006 Jul;19(7):937-43. doi: 10.1021/tx0600595. Chem Res Toxicol. 2006. PMID: 16841962

6

Myeloperoxidase-dependent oxidation of etoposide in human myeloid progenitor CD34+ cells.

Vlasova II, Feng WH, Goff JP, Giorgianni A, Do D, Gollin SM, Lewis DW, Kagan VE, Yalowich JC. Vlasova II, et al. Mol Pharmacol. 2011 Mar;79(3):479-87. doi: 10.1124/mol.110.068718. Epub 2010 Nov 19. Mol Pharmacol. 2011. PMID: 21097707 Free PMC article.

7

Structure-based design, synthesis and biological testing of piperazine-linked bis-epipodophyllotoxin etoposide analogs.

Yadav AA, Chee GL, Wu X, Patel D, Yalowich JC, Hasinoff BB. Yadav AA, et al. Bioorg Med Chem. 2015 Jul 1;23(13):3542-51. doi: 10.1016/j.bmc.2015.04.022. Epub 2015 Apr 16. Bioorg Med Chem. 2015. PMID: 25922181 Free PMC article.

8

Mechanisms of Action and Reduced Cardiotoxicity of Pixantrone; a Topoisomerase II Targeting Agent with Cellular Selectivity for the Topoisomerase IIα Isoform.

Hasinoff BB, Wu X, Patel D, Kanagasabai R, Karmahapatra S, Yalowich JC. Hasinoff BB, et al. J Pharmacol Exp Ther. 2016 Feb;356(2):397-409. doi: 10.1124/jpet.115.228650. Epub 2015 Dec 11. J Pharmacol Exp Ther. 2016. PMID: 26660439 Free PMC article.

9

A diazirine-based photoaffinity etoposide probe for labeling topoisomerase II.

Chee GL, Yalowich JC, Bodner A, Wu X, Hasinoff BB. Chee GL, et al. Bioorg Med Chem. 2010 Jan 15;18(2):830-8. doi: 10.1016/j.bmc.2009.11.048. Epub 2009 Nov 27. Bioorg Med Chem. 2010. PMID: 20006518 Free PMC article.

10

Design, synthesis and biological evaluation of a novel series of anthrapyrazoles linked with netropsin-like oligopyrrole carboxamides as anticancer agents.

Zhang R, Wu X, Guziec LJ, Guziec FS, Chee GL, Yalowich JC, Hasinoff BB. Zhang R, et al. Bioorg Med Chem. 2010 Jun 1;18(11):3974-84. doi: 10.1016/j.bmc.2010.04.028. Epub 2010 Apr 18. Bioorg Med Chem. 2010. PMID: 20471276 Free PMC article.

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