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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2006 2
2007 1
2008 4
2009 7
2010 2
2011 5
2012 3
2013 8
2014 2
2015 1
2016 1
2021 0
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35 results
Results by year
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Page 1
AKT/PKB signaling: navigating downstream.
Manning BD, Cantley LC. Manning BD, et al. Cell. 2007 Jun 29;129(7):1261-74. doi: 10.1016/j.cell.2007.06.009. Cell. 2007. PMID: 17604717 Free PMC article. Review.
The TSC-mTOR pathway regulates macrophage polarization.
Byles V, Covarrubias AJ, Ben-Sahra I, Lamming DW, Sabatini DM, Manning BD, Horng T. Byles V, et al. Nat Commun. 2013;4:2834. doi: 10.1038/ncomms3834. Nat Commun. 2013. PMID: 24280772 Free PMC article.
Activation of a metabolic gene regulatory network downstream of mTOR complex 1.
Düvel K, Yecies JL, Menon S, Raman P, Lipovsky AI, Souza AL, Triantafellow E, Ma Q, Gorski R, Cleaver S, Vander Heiden MG, MacKeigan JP, Finan PM, Clish CB, Murphy LO, Manning BD. Düvel K, et al. Mol Cell. 2010 Jul 30;39(2):171-83. doi: 10.1016/j.molcel.2010.06.022. Mol Cell. 2010. PMID: 20670887 Free PMC article.
Coordinated regulation of protein synthesis and degradation by mTORC1.
Zhang Y, Nicholatos J, Dreier JR, Ricoult SJ, Widenmaier SB, Hotamisligil GS, Kwiatkowski DJ, Manning BD. Zhang Y, et al. Nature. 2014 Sep 18;513(7518):440-3. doi: 10.1038/nature13492. Epub 2014 Jul 13. Nature. 2014. PMID: 25043031 Free PMC article.
The TSC1-TSC2 complex: a molecular switchboard controlling cell growth.
Huang J, Manning BD. Huang J, et al. Biochem J. 2008 Jun 1;412(2):179-90. doi: 10.1042/BJ20080281. Biochem J. 2008. PMID: 18466115 Free PMC article. Review.
Stimulation of de novo pyrimidine synthesis by growth signaling through mTOR and S6K1.
Ben-Sahra I, Howell JJ, Asara JM, Manning BD. Ben-Sahra I, et al. Science. 2013 Mar 15;339(6125):1323-8. doi: 10.1126/science.1228792. Epub 2013 Feb 21. Science. 2013. PMID: 23429703 Free PMC article.
TBC1D7 is a third subunit of the TSC1-TSC2 complex upstream of mTORC1.
Dibble CC, Elis W, Menon S, Qin W, Klekota J, Asara JM, Finan PM, Kwiatkowski DJ, Murphy LO, Manning BD. Dibble CC, et al. Mol Cell. 2012 Aug 24;47(4):535-46. doi: 10.1016/j.molcel.2012.06.009. Epub 2012 Jul 12. Mol Cell. 2012. PMID: 22795129 Free PMC article.
Spatial control of the TSC complex integrates insulin and nutrient regulation of mTORC1 at the lysosome.
Menon S, Dibble CC, Talbott G, Hoxhaj G, Valvezan AJ, Takahashi H, Cantley LC, Manning BD. Menon S, et al. Cell. 2014 Feb 13;156(4):771-85. doi: 10.1016/j.cell.2013.11.049. Cell. 2014. PMID: 24529379 Free PMC article.
mTORC1 signaling activates NRF1 to increase cellular proteasome levels.
Zhang Y, Manning BD. Zhang Y, et al. Cell Cycle. 2015;14(13):2011-7. doi: 10.1080/15384101.2015.1044188. Epub 2015 May 27. Cell Cycle. 2015. PMID: 26017155 Free PMC article. Review.
mTORC1 status dictates tumor response to targeted therapeutics.
Kelsey I, Manning BD. Kelsey I, et al. Sci Signal. 2013 Sep 24;6(294):pe31. doi: 10.1126/scisignal.2004632. Sci Signal. 2013. PMID: 24065143 Review.
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