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Targeting PAK1.

Semenova G, Chernoff J. Semenova G, et al. Biochem Soc Trans. 2017 Feb 8;45(1):79-88. doi: 10.1042/BST20160134. Biochem Soc Trans. 2017. PMID: 28202661 Free PMC article. Review.

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Pak2 as a Novel Therapeutic Target for Cardioprotective Endoplasmic Reticulum Stress Response.

Binder P, Wang S, Radu M, Zin M, Collins L, Khan S, Li Y, Sekeres K, Humphreys N, Swanton E, Reid A, Pu F, Oceandy D, Guan K, Hille SS, Frey N, Müller OJ, Cartwright EJ, Chernoff J, Wang X, Liu W. Binder P, et al. Circ Res. 2019 Mar;124(5):696-711. doi: 10.1161/CIRCRESAHA.118.312829. Circ Res. 2019. PMID: 30620686 Free PMC article.

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RAC1 as a Therapeutic Target in Malignant Melanoma.

Cannon AC, Uribe-Alvarez C, Chernoff J. Cannon AC, et al. Trends Cancer. 2020 Jun;6(6):478-488. doi: 10.1016/j.trecan.2020.02.021. Epub 2020 Mar 18. Trends Cancer. 2020. PMID: 32460002 Free PMC article. Review.

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Regulation of MST complexes and activity via SARAH domain modifications.

Karchugina S, Benton D, Chernoff J. Karchugina S, et al. Biochem Soc Trans. 2021 Apr 30;49(2):675-683. doi: 10.1042/BST20200559. Biochem Soc Trans. 2021. PMID: 33860801 Review.

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Regulation of mammalian Ste20 (Mst) kinases.

Rawat SJ, Chernoff J. Rawat SJ, et al. Trends Biochem Sci. 2015 Mar;40(3):149-56. doi: 10.1016/j.tibs.2015.01.001. Epub 2015 Feb 6. Trends Biochem Sci. 2015. PMID: 25665457 Free PMC article. Review.

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Hras helps hippo heterodimerize to evade tumor suppression.

Araiza-Olivera D, Chernoff J. Araiza-Olivera D, et al. Small GTPases. 2018 Jul 4;9(4):327-331. doi: 10.1080/21541248.2016.1228794. Epub 2016 Sep 20. Small GTPases. 2018. PMID: 27560370 Free PMC article. Review.

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PAK signalling during the development and progression of cancer.

Radu M, Semenova G, Kosoff R, Chernoff J. Radu M, et al. Nat Rev Cancer. 2014 Jan;14(1):13-25. doi: 10.1038/nrc3645. Nat Rev Cancer. 2014. PMID: 24505617 Free PMC article. Review.

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A New Rho(d) Map to Diffuse Gastric Cancer.

Benton D, Chernoff J. Benton D, et al. Cancer Discov. 2020 Feb;10(2):182-184. doi: 10.1158/2159-8290.CD-19-1327. Cancer Discov. 2020. PMID: 32024682 Free PMC article.

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Connecting molecular pathways to hereditary cancer risk syndromes.

Testa JR, Malkin D, Schiffman JD. Testa JR, et al. Am Soc Clin Oncol Educ Book. 2013:81-90. doi: 10.14694/EdBook_AM.2013.33.81. Am Soc Clin Oncol Educ Book. 2013. PMID: 23714463 Free PMC article. Review.

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Nonsteroidal sulfamate derivatives as new therapeutic approaches for Neurofibromatosis 2 (NF2).

Shen YC, Arellano-Garcia C, Menjivar RE, Jewett EM, Dohle W, Karchugina S, Chernoff J, Potter BVL, Barald KF. Shen YC, et al. BMC Pharmacol Toxicol. 2019 Nov 15;20(1):67. doi: 10.1186/s40360-019-0369-8. BMC Pharmacol Toxicol. 2019. PMID: 31730023 Free PMC article.

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