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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2011 2
2012 2
2013 3
2014 2
2015 4
2016 3
2017 5
2018 3
2019 1
2020 0
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22 results
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Page 1
Chromosomal instability drives metastasis through a cytosolic DNA response.
Bakhoum SF, Ngo B, Laughney AM, Cavallo JA, Murphy CJ, Ly P, Shah P, Sriram RK, Watkins TBK, Taunk NK, Duran M, Pauli C, Shaw C, Chadalavada K, Rajasekhar VK, Genovese G, Venkatesan S, Birkbak NJ, McGranahan N, Lundquist M, LaPlant Q, Healey JH, Elemento O, Chung CH, Lee NY, Imielenski M, Nanjangud G, Pe'er D, Cleveland DW, Powell SN, Lammerding J, Swanton C, Cantley LC. Bakhoum SF, et al. Nature. 2018 Jan 25;553(7689):467-472. doi: 10.1038/nature25432. Epub 2018 Jan 17. Nature. 2018. PMID: 29342134 Free PMC article.
BRCA1 and BRCA2: different roles in a common pathway of genome protection.
Roy R, Chun J, Powell SN. Roy R, et al. Nat Rev Cancer. 2011 Dec 23;12(1):68-78. doi: 10.1038/nrc3181. Nat Rev Cancer. 2011. PMID: 22193408 Free PMC article. Review.
PARP Inhibitor Activity Correlates with SLFN11 Expression and Demonstrates Synergy with Temozolomide in Small Cell Lung Cancer.
Lok BH, Gardner EE, Schneeberger VE, Ni A, Desmeules P, Rekhtman N, de Stanchina E, Teicher BA, Riaz N, Powell SN, Poirier JT, Rudin CM. Lok BH, et al. Clin Cancer Res. 2017 Jan 15;23(2):523-535. doi: 10.1158/1078-0432.CCR-16-1040. Epub 2016 Jul 20. Clin Cancer Res. 2017. PMID: 27440269 Free PMC article.
Pan-cancer analysis of bi-allelic alterations in homologous recombination DNA repair genes.
Riaz N, Blecua P, Lim RS, Shen R, Higginson DS, Weinhold N, Norton L, Weigelt B, Powell SN, Reis-Filho JS. Riaz N, et al. Nat Commun. 2017 Oct 11;8(1):857. doi: 10.1038/s41467-017-00921-w. Nat Commun. 2017. PMID: 29021619 Free PMC article.
Androgen receptor signaling regulates DNA repair in prostate cancers.
Polkinghorn WR, Parker JS, Lee MX, Kass EM, Spratt DE, Iaquinta PJ, Arora VK, Yen WF, Cai L, Zheng D, Carver BS, Chen Y, Watson PA, Shah NP, Fujisawa S, Goglia AG, Gopalan A, Hieronymus H, Wongvipat J, Scardino PT, Zelefsky MJ, Jasin M, Chaudhuri J, Powell SN, Sawyers CL. Polkinghorn WR, et al. Cancer Discov. 2013 Nov;3(11):1245-53. doi: 10.1158/2159-8290.CD-13-0172. Epub 2013 Sep 11. Cancer Discov. 2013. PMID: 24027196 Free PMC article.
A new role for a tumor-suppressing protein.
Setton JS, Powell SN. Setton JS, et al. Elife. 2018 Mar 1;7:e35111. doi: 10.7554/eLife.35111. Elife. 2018. PMID: 29493507 Free PMC article.
The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma.
Bott M, Brevet M, Taylor BS, Shimizu S, Ito T, Wang L, Creaney J, Lake RA, Zakowski MF, Reva B, Sander C, Delsite R, Powell S, Zhou Q, Shen R, Olshen A, Rusch V, Ladanyi M. Bott M, et al. Nat Genet. 2011 Jun 5;43(7):668-72. doi: 10.1038/ng.855. Nat Genet. 2011. PMID: 21642991 Free PMC article.
Single-dose radiotherapy disables tumor cell homologous recombination via ischemia/reperfusion injury.
Bodo S, Campagne C, Thin TH, Higginson DS, Vargas HA, Hua G, Fuller JD, Ackerstaff E, Russell J, Zhang Z, Klingler S, Cho H, Kaag MG, Mazaheri Y, Rimner A, Manova-Todorova K, Epel B, Zatcky J, Cleary CR, Rao SS, Yamada Y, Zelefsky MJ, Halpern HJ, Koutcher JA, Cordon-Cardo C, Greco C, Haimovitz-Friedman A, Sala E, Powell SN, Kolesnick R, Fuks Z. Bodo S, et al. J Clin Invest. 2019 Feb 1;129(2):786-801. doi: 10.1172/JCI97631. Epub 2019 Jan 14. J Clin Invest. 2019. PMID: 30480549 Free PMC article.
Mitotic DNA Damage Response: At the Crossroads of Structural and Numerical Cancer Chromosome Instabilities.
Bakhoum SF, Kabeche L, Compton DA, Powell SN, Bastians H. Bakhoum SF, et al. Trends Cancer. 2017 Mar;3(3):225-234. doi: 10.1016/j.trecan.2017.02.001. Epub 2017 Feb 28. Trends Cancer. 2017. PMID: 28718433 Free PMC article. Review.
Inhibition of non-homologous end joining in Fanconi Anemia cells results in rescue of survival after interstrand crosslinks but sensitization to replication associated double-strand breaks.
Eccles LJ, Bell AC, Powell SN. Eccles LJ, et al. DNA Repair (Amst). 2018 Apr;64:1-9. doi: 10.1016/j.dnarep.2018.02.003. Epub 2018 Feb 10. DNA Repair (Amst). 2018. PMID: 29459202 Free PMC article.
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