R01 DA020032/DA/NIDA NIH HHS/United States[Grant Number] - Search Results

Year	Number of Results
2006	2
2008	3
2009	4
2010	3
2011	3
2012	1
2022	0

1

Progress in elucidating the structural and dynamic character of G Protein-Coupled Receptor oligomers for use in drug discovery.

Bortolato A, Mobarec JC, Provasi D, Filizola M. Bortolato A, et al. Curr Pharm Des. 2009;15(35):4017-25. doi: 10.2174/138161209789824768. Curr Pharm Des. 2009. PMID: 20028319 Free PMC article. Review.

2

Increasingly accurate dynamic molecular models of G-protein coupled receptor oligomers: Panacea or Pandora's box for novel drug discovery?

Filizola M. Filizola M. Life Sci. 2010 Apr 10;86(15-16):590-7. doi: 10.1016/j.lfs.2009.05.004. Epub 2009 May 22. Life Sci. 2010. PMID: 19465029 Free PMC article. Review.

3

Putative active states of a prototypic g-protein-coupled receptor from biased molecular dynamics.

Provasi D, Filizola M. Provasi D, et al. Biophys J. 2010 May 19;98(10):2347-55. doi: 10.1016/j.bpj.2010.01.047. Biophys J. 2010. PMID: 20483344 Free PMC article.

4

Assessing the relative stability of dimer interfaces in g protein-coupled receptors.

Johnston JM, Wang H, Provasi D, Filizola M. Johnston JM, et al. PLoS Comput Biol. 2012;8(8):e1002649. doi: 10.1371/journal.pcbi.1002649. Epub 2012 Aug 16. PLoS Comput Biol. 2012. PMID: 22916005 Free PMC article.

5

Making structural sense of dimerization interfaces of delta opioid receptor homodimers.

Johnston JM, Aburi M, Provasi D, Bortolato A, Urizar E, Lambert NA, Javitch JA, Filizola M. Johnston JM, et al. Biochemistry. 2011 Mar 15;50(10):1682-90. doi: 10.1021/bi101474v. Epub 2011 Feb 9. Biochemistry. 2011. PMID: 21261298 Free PMC article.

6

Lessons from free energy simulations of delta-opioid receptor homodimers involving the fourth transmembrane helix.

Provasi D, Johnston JM, Filizola M. Provasi D, et al. Biochemistry. 2010 Aug 10;49(31):6771-6. doi: 10.1021/bi100686t. Biochemistry. 2010. PMID: 20617813 Free PMC article.

7

Modern homology modeling of G-protein coupled receptors: which structural template to use?

Mobarec JC, Sanchez R, Filizola M. Mobarec JC, et al. J Med Chem. 2009 Aug 27;52(16):5207-16. doi: 10.1021/jm9005252. J Med Chem. 2009. PMID: 19627087 Free PMC article.

8

Differential response to morphine of the oligomeric state of μ-opioid in the presence of δ-opioid receptors.

Golebiewska U, Johnston JM, Devi L, Filizola M, Scarlata S. Golebiewska U, et al. Biochemistry. 2011 Apr 12;50(14):2829-37. doi: 10.1021/bi101701x. Epub 2011 Mar 17. Biochemistry. 2011. PMID: 21361347 Free PMC article.

9

Showcasing modern molecular dynamics simulations of membrane proteins through G protein-coupled receptors.

Johnston JM, Filizola M. Johnston JM, et al. Curr Opin Struct Biol. 2011 Aug;21(4):552-8. doi: 10.1016/j.sbi.2011.06.008. Epub 2011 Jul 19. Curr Opin Struct Biol. 2011. PMID: 21764295 Free PMC article. Review.

10

Mutations affecting the oligomerization interface of G-protein-coupled receptors revealed by a novel de novo protein design framework.

Taylor MS, Fung HK, Rajgaria R, Filizola M, Weinstein H, Floudas CA. Taylor MS, et al. Biophys J. 2008 Apr 1;94(7):2470-81. doi: 10.1529/biophysj.107.117622. Epub 2008 Jan 4. Biophys J. 2008. PMID: 18178645 Free PMC article.

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