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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1997 1
1999 4
2000 1
2002 1
2003 4
2004 1
2006 2
2007 3
2008 4
2009 3
2010 6
2011 3
2012 8
2013 5
2014 4
2015 7
2016 10
2017 9
2018 12
2019 8
2020 4
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97 results
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Page 1
Type 2 diabetes mellitus.
DeFronzo RA, Ferrannini E, Groop L, Henry RR, Herman WH, Holst JJ, Hu FB, Kahn CR, Raz I, Shulman GI, Simonson DC, Testa MA, Weiss R. DeFronzo RA, et al. Nat Rev Dis Primers. 2015 Jul 23;1:15019. doi: 10.1038/nrdp.2015.19. Nat Rev Dis Primers. 2015. PMID: 27189025 Review.
Adipose-derived circulating miRNAs regulate gene expression in other tissues.
Thomou T, Mori MA, Dreyfuss JM, Konishi M, Sakaguchi M, Wolfrum C, Rao TN, Winnay JN, Garcia-Martin R, Grinspoon SK, Gorden P, Kahn CR. Thomou T, et al. Nature. 2017 Feb 23;542(7642):450-455. doi: 10.1038/nature21365. Epub 2017 Feb 15. Nature. 2017. PMID: 28199304 Free PMC article.
Insulin action in brain regulates systemic metabolism and brain function.
Kleinridders A, Ferris HA, Cai W, Kahn CR. Kleinridders A, et al. Diabetes. 2014 Jul;63(7):2232-43. doi: 10.2337/db14-0568. Epub 2014 Jun 15. Diabetes. 2014. PMID: 24931034 Free PMC article. Review.
Diabetes primes neutrophils to undergo NETosis, which impairs wound healing.
Wong SL, Demers M, Martinod K, Gallant M, Wang Y, Goldfine AB, Kahn CR, Wagner DD. Wong SL, et al. Nat Med. 2015 Jul;21(7):815-9. doi: 10.1038/nm.3887. Epub 2015 Jun 15. Nat Med. 2015. PMID: 26076037 Free PMC article.
Astrocytic Insulin Signaling Couples Brain Glucose Uptake with Nutrient Availability.
García-Cáceres C, Quarta C, Varela L, Gao Y, Gruber T, Legutko B, Jastroch M, Johansson P, Ninkovic J, Yi CX, Le Thuc O, Szigeti-Buck K, Cai W, Meyer CW, Pfluger PT, Fernandez AM, Luquet S, Woods SC, Torres-Alemán I, Kahn CR, Götz M, Horvath TL, Tschöp MH. García-Cáceres C, et al. Cell. 2016 Aug 11;166(4):867-880. doi: 10.1016/j.cell.2016.07.028. Cell. 2016. PMID: 27518562 Free article.
FoxK1 and FoxK2 in insulin regulation of cellular and mitochondrial metabolism.
Sakaguchi M, Cai W, Wang CH, Cederquist CT, Damasio M, Homan EP, Batista T, Ramirez AK, Gupta MK, Steger M, Wewer Albrechtsen NJ, Singh SK, Araki E, Mann M, Enerbäck S, Kahn CR. Sakaguchi M, et al. Nat Commun. 2019 Apr 5;10(1):1582. doi: 10.1038/s41467-019-09418-0. Nat Commun. 2019. PMID: 30952843 Free PMC article.
Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling.
Softic S, Gupta MK, Wang GX, Fujisaka S, O'Neill BT, Rao TN, Willoughby J, Harbison C, Fitzgerald K, Ilkayeva O, Newgard CB, Cohen DE, Kahn CR. Softic S, et al. J Clin Invest. 2017 Nov 1;127(11):4059-4074. doi: 10.1172/JCI94585. Epub 2017 Oct 3. J Clin Invest. 2017. PMID: 28972537 Free PMC article.
FoxO Transcription Factors Are Critical Regulators of Diabetes-Related Muscle Atrophy.
O'Neill BT, Bhardwaj G, Penniman CM, Krumpoch MT, Suarez Beltran PA, Klaus K, Poro K, Li M, Pan H, Dreyfuss JM, Nair KS, Kahn CR. O'Neill BT, et al. Diabetes. 2019 Mar;68(3):556-570. doi: 10.2337/db18-0416. Epub 2018 Dec 6. Diabetes. 2019. PMID: 30523026 Free PMC article.
Gut microbiota modulate neurobehavior through changes in brain insulin sensitivity and metabolism.
Soto M, Herzog C, Pacheco JA, Fujisaka S, Bullock K, Clish CB, Kahn CR. Soto M, et al. Mol Psychiatry. 2018 Dec;23(12):2287-2301. doi: 10.1038/s41380-018-0086-5. Epub 2018 Jun 18. Mol Psychiatry. 2018. PMID: 29910467 Free PMC article.
Insulin regulates astrocyte gliotransmission and modulates behavior.
Cai W, Xue C, Sakaguchi M, Konishi M, Shirazian A, Ferris HA, Li ME, Yu R, Kleinridders A, Pothos EN, Kahn CR. Cai W, et al. J Clin Invest. 2018 Jul 2;128(7):2914-2926. doi: 10.1172/JCI99366. Epub 2018 Jun 4. J Clin Invest. 2018. PMID: 29664737 Free PMC article.
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