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Early sympathetic islet neuropathy in autoimmune diabetes: lessons learned and opportunities for investigation.

Mundinger TO, Taborsky GJ Jr. Mundinger TO, et al. Diabetologia. 2016 Oct;59(10):2058-67. doi: 10.1007/s00125-016-4026-0. Epub 2016 Jun 24. Diabetologia. 2016. PMID: 27342407 Free PMC article. Review.

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The search for the mechanism of early sympathetic islet neuropathy in autoimmune diabetes.

Taborsky GJ Jr, Mei Q, Hackney DJ, Mundinger TO. Taborsky GJ Jr, et al. Diabetes Obes Metab. 2014 Sep;16 Suppl 1(0 1):96-101. doi: 10.1111/dom.12341. Diabetes Obes Metab. 2014. PMID: 25200302 Free PMC article. Review.

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Minireview: The role of the autonomic nervous system in mediating the glucagon response to hypoglycemia.

Taborsky GJ Jr, Mundinger TO. Taborsky GJ Jr, et al. Endocrinology. 2012 Mar;153(3):1055-62. doi: 10.1210/en.2011-2040. Epub 2012 Feb 7. Endocrinology. 2012. PMID: 22315452 Free PMC article. Review.

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Islets have a lot of nerve! Or do they?

Taborsky GJ Jr. Taborsky GJ Jr. Cell Metab. 2011 Jul 6;14(1):5-6. doi: 10.1016/j.cmet.2011.06.004. Cell Metab. 2011. PMID: 21723498 Free PMC article.

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Human Type 1 Diabetes Is Characterized by an Early, Marked, Sustained, and Islet-Selective Loss of Sympathetic Nerves.

Mundinger TO, Mei Q, Foulis AK, Fligner CL, Hull RL, Taborsky GJ Jr. Mundinger TO, et al. Diabetes. 2016 Aug;65(8):2322-30. doi: 10.2337/db16-0284. Epub 2016 May 13. Diabetes. 2016. PMID: 27207540 Free PMC article.

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Evidence That the Sympathetic Nervous System Elicits Rapid, Coordinated, and Reciprocal Adjustments of Insulin Secretion and Insulin Sensitivity During Cold Exposure.

Morton GJ, Muta K, Kaiyala KJ, Rojas JM, Scarlett JM, Matsen ME, Nelson JT, Acharya NK, Piccinini F, Stefanovski D, Bergman RN, Taborsky GJ Jr, Kahn SE, Schwartz MW. Morton GJ, et al. Diabetes. 2017 Apr;66(4):823-834. doi: 10.2337/db16-1351. Epub 2017 Jan 23. Diabetes. 2017. PMID: 28115396 Free PMC article.

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Leptin deficiency causes insulin resistance induced by uncontrolled diabetes.

German JP, Wisse BE, Thaler JP, Oh-I S, Sarruf DA, Ogimoto K, Kaiyala KJ, Fischer JD, Matsen ME, Taborsky GJ Jr, Schwartz MW, Morton GJ. German JP, et al. Diabetes. 2010 Jul;59(7):1626-34. doi: 10.2337/db09-1918. Epub 2010 Apr 27. Diabetes. 2010. PMID: 20424233 Free PMC article.

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Evidence That in Uncontrolled Diabetes, Hyperglucagonemia Is Required for Ketosis but Not for Increased Hepatic Glucose Production or Hyperglycemia.

Meek TH, Dorfman MD, Matsen ME, Fischer JD, Cubelo A, Kumar MR, Taborsky GJ Jr, Morton GJ. Meek TH, et al. Diabetes. 2015 Jul;64(7):2376-87. doi: 10.2337/db14-1562. Epub 2015 Jan 29. Diabetes. 2015. PMID: 25633417 Free PMC article.

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Leptin activates a novel CNS mechanism for insulin-independent normalization of severe diabetic hyperglycemia.

German JP, Thaler JP, Wisse BE, Oh-I S, Sarruf DA, Matsen ME, Fischer JD, Taborsky GJ Jr, Schwartz MW, Morton GJ. German JP, et al. Endocrinology. 2011 Feb;152(2):394-404. doi: 10.1210/en.2010-0890. Epub 2010 Dec 15. Endocrinology. 2011. PMID: 21159853 Free PMC article.

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Leptin action in the ventromedial hypothalamic nucleus is sufficient, but not necessary, to normalize diabetic hyperglycemia.

Meek TH, Matsen ME, Dorfman MD, Guyenet SJ, Damian V, Nguyen HT, Taborsky GJ Jr, Morton GJ. Meek TH, et al. Endocrinology. 2013 Sep;154(9):3067-76. doi: 10.1210/en.2013-1328. Epub 2013 Jun 19. Endocrinology. 2013. PMID: 23782941 Free PMC article.

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