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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 1
2002 3
2003 1
2004 3
2005 3
2006 1
2007 3
2008 4
2009 5
2010 6
2011 4
2012 3
2013 4
2014 3
2015 3
2016 3
2017 5
2018 6
2019 4
2020 3
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Search Results

60 results
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Page 1
Structural mechanisms of CFTR function and dysfunction.
Hwang TC, Yeh JT, Zhang J, Yu YC, Yeh HI, Destefano S. Hwang TC, et al. J Gen Physiol. 2018 Apr 2;150(4):539-570. doi: 10.1085/jgp.201711946. Epub 2018 Mar 26. J Gen Physiol. 2018. PMID: 29581173 Free PMC article. Review.
Positional effects of premature termination codons on the biochemical and biophysical properties of CFTR.
Yeh JT, Hwang TC. Yeh JT, et al. J Physiol. 2020 Feb;598(3):517-541. doi: 10.1113/JP278418. Epub 2019 Nov 2. J Physiol. 2020. PMID: 31585024
CFTR: New insights into structure and function and implications for modulation by small molecules.
Kleizen B, Hunt JF, Callebaut I, Hwang TC, Sermet-Gaudelus I, Hafkemeyer S, Sheppard DN. Kleizen B, et al. J Cyst Fibros. 2020 Mar;19 Suppl 1:S19-S24. doi: 10.1016/j.jcf.2019.10.021. Epub 2019 Nov 21. J Cyst Fibros. 2020. PMID: 31759907
Identifying the molecular target sites for CFTR potentiators GLPG1837 and VX-770.
Yeh HI, Qiu L, Sohma Y, Conrath K, Zou X, Hwang TC. Yeh HI, et al. J Gen Physiol. 2019 Jul 1;151(7):912-928. doi: 10.1085/jgp.201912360. Epub 2019 Jun 4. J Gen Physiol. 2019. PMID: 31164398 Free PMC article.
CFTR potentiators: from bench to bedside.
Jih KY, Lin WY, Sohma Y, Hwang TC. Jih KY, et al. Curr Opin Pharmacol. 2017 Jun;34:98-104. doi: 10.1016/j.coph.2017.09.015. Epub 2017 Nov 5. Curr Opin Pharmacol. 2017. PMID: 29073476 Free PMC article. Review.
Ion channels as targets to treat cystic fibrosis lung disease.
Martin SL, Saint-Criq V, Hwang TC, Csanády L. Martin SL, et al. J Cyst Fibros. 2018 Mar;17(2S):S22-S27. doi: 10.1016/j.jcf.2017.10.006. Epub 2017 Nov 6. J Cyst Fibros. 2018. PMID: 29102290 Free article. Review.
A common mechanism for CFTR potentiators.
Yeh HI, Sohma Y, Conrath K, Hwang TC. Yeh HI, et al. J Gen Physiol. 2017 Dec 4;149(12):1105-1118. doi: 10.1085/jgp.201711886. Epub 2017 Oct 27. J Gen Physiol. 2017. PMID: 29079713 Free PMC article.
Nonequilibrium gating of CFTR on an equilibrium theme.
Jih KY, Hwang TC. Jih KY, et al. Physiology (Bethesda). 2012 Dec;27(6):351-61. doi: 10.1152/physiol.00026.2012. Physiology (Bethesda). 2012. PMID: 23223629 Free PMC article. Review.
Physiological and pharmacological characterization of the N1303K mutant CFTR.
DeStefano S, Gees M, Hwang TC. DeStefano S, et al. J Cyst Fibros. 2018 Sep;17(5):573-581. doi: 10.1016/j.jcf.2018.05.011. Epub 2018 Jun 7. J Cyst Fibros. 2018. PMID: 29887518 Free PMC article.
Cystic fibrosis research topics featured at the 14th ECFS Basic Science Conference: Chairman's summary.
Mall MA, Hwang TC, Braakman I. Mall MA, et al. J Cyst Fibros. 2018 Mar;17(2S):S1-S4. doi: 10.1016/j.jcf.2017.11.008. Epub 2017 Dec 9. J Cyst Fibros. 2018. PMID: 29229473 Free article. Review.
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