R01 DK069575/DK/NIDDK NIH HHS/United States[Grant Number] - Search Results

Year	Number of Results
2006	3
2007	3
2008	4
2009	4
2010	4
2011	2
2012	3
2013	6
2014	2
2015	4
2016	5
2018	4
2019	2
2020	5
2021	5
2022	1

1

Regulation of glucose homeostasis by GLP-1.

Nadkarni P, Chepurny OG, Holz GG. Nadkarni P, et al. Prog Mol Biol Transl Sci. 2014;121:23-65. doi: 10.1016/B978-0-12-800101-1.00002-8. Prog Mol Biol Transl Sci. 2014. PMID: 24373234 Free PMC article. Review.

2

Role of phospholipase Cε in physiological phosphoinositide signaling networks.

Smrcka AV, Brown JH, Holz GG. Smrcka AV, et al. Cell Signal. 2012 Jun;24(6):1333-43. doi: 10.1016/j.cellsig.2012.01.009. Epub 2012 Jan 20. Cell Signal. 2012. PMID: 22286105 Free PMC article. Review.

3

Synthesis, Optimization, and Biological Evaluation of Corrinated Conjugates of the GLP-1R Agonist Exendin-4.

Tinsley IC, Borner T, Swanson ML, Chepurny OG, Doebley SA, Kamat V, Sweet IR, Holz GG, Hayes MR, De Jonghe BC, Doyle RP. Tinsley IC, et al. J Med Chem. 2021 Mar 25;64(6):3479-3492. doi: 10.1021/acs.jmedchem.1c00185. Epub 2021 Mar 6. J Med Chem. 2021. PMID: 33677970 Free PMC article.

4

Cell physiology of cAMP sensor Epac.

Holz GG, Kang G, Harbeck M, Roe MW, Chepurny OG. Holz GG, et al. J Physiol. 2006 Nov 15;577(Pt 1):5-15. doi: 10.1113/jphysiol.2006.119644. Epub 2006 Sep 14. J Physiol. 2006. PMID: 16973695 Free PMC article. Review.

5

Leptin-stimulated KATP channel trafficking: a new paradigm for β-cell stimulus-secretion coupling?

Holz GG, Chepurny OG, Leech CA. Holz GG, et al. Islets. 2013 Sep-Dec;5(5):229-32. doi: 10.4161/isl.26958. Epub 2013 Nov 8. Islets. 2013. PMID: 24213304 Free PMC article. Review.

6

Therapeutic potential of α7 nicotinic acetylcholine receptor agonists to combat obesity, diabetes, and inflammation.

Xie H, Yepuri N, Meng Q, Dhawan R, Leech CA, Chepurny OG, Holz GG, Cooney RN. Xie H, et al. Rev Endocr Metab Disord. 2020 Dec;21(4):431-447. doi: 10.1007/s11154-020-09584-3. Epub 2020 Aug 26. Rev Endocr Metab Disord. 2020. PMID: 32851581 Free PMC article. Review.

7

Corrination of a GLP-1 Receptor Agonist for Glycemic Control without Emesis.

Borner T, Workinger JL, Tinsley IC, Fortin SM, Stein LM, Chepurny OG, Holz GG, Wierzba AJ, Gryko D, Nexø E, Shaulson ED, Bamezai A, Da Silva VAR, De Jonghe BC, Hayes MR, Doyle RP. Borner T, et al. Cell Rep. 2020 Jun 16;31(11):107768. doi: 10.1016/j.celrep.2020.107768. Cell Rep. 2020. PMID: 32553160 Free PMC article.

8

Synthesis, in vitro biological investigation, and molecular dynamics simulations of thiazolopyrimidine based compounds as corticotrophin releasing factor receptor-1 antagonists.

Elgiushy HR, Abou-Taleb NA, Holz GG, Chepurny OG, Pirmettis I, Kakabakos S, Karageorgos V, Liapakis G, Albohy A, Abouzid KAM, Hammad SF. Elgiushy HR, et al. Bioorg Chem. 2021 Sep;114:105079. doi: 10.1016/j.bioorg.2021.105079. Epub 2021 Jun 10. Bioorg Chem. 2021. PMID: 34174633

9

Design and Evaluation of Peptide Dual-Agonists of GLP-1 and NPY2 Receptors for Glucoregulation and Weight Loss with Mitigated Nausea and Emesis.

Milliken BT, Elfers C, Chepurny OG, Chichura KS, Sweet IR, Borner T, Hayes MR, De Jonghe BC, Holz GG, Roth CL, Doyle RP. Milliken BT, et al. J Med Chem. 2021 Jan 28;64(2):1127-1138. doi: 10.1021/acs.jmedchem.0c01783. Epub 2021 Jan 15. J Med Chem. 2021. PMID: 33449689 Free PMC article.

10

Molecular physiology of glucagon-like peptide-1 insulin secretagogue action in pancreatic β cells.

Leech CA, Dzhura I, Chepurny OG, Kang G, Schwede F, Genieser HG, Holz GG. Leech CA, et al. Prog Biophys Mol Biol. 2011 Nov;107(2):236-47. doi: 10.1016/j.pbiomolbio.2011.07.005. Epub 2011 Jul 19. Prog Biophys Mol Biol. 2011. PMID: 21782840 Free PMC article. Review.

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