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LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation.
Mol Cell. 2013 Feb 7;49(3):558-70. doi: 10.1016/j.molcel.2012.11.019. Epub 2012 Dec 20.
Mol Cell. 2013.
PMID: 23260659
Free PMC article.
Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma.
Lian CG, Xu Y, Ceol C, Wu F, Larson A, Dresser K, Xu W, Tan L, Hu Y, Zhan Q, Lee CW, Hu D, Lian BQ, Kleffel S, Yang Y, Neiswender J, Khorasani AJ, Fang R, Lezcano C, Duncan LM, Scolyer RA, Thompson JF, Kakavand H, Houvras Y, Zon LI, Mihm MC Jr, Kaiser UB, Schatton T, Woda BA, Murphy GF, Shi YG.
Lian CG, et al.
Cell. 2012 Sep 14;150(6):1135-46. doi: 10.1016/j.cell.2012.07.033.
Cell. 2012.
PMID: 22980977
Free PMC article.
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Genome-wide regulation of 5hmC, 5mC, and gene expression by Tet1 hydroxylase in mouse embryonic stem cells.
Xu Y, Wu F, Tan L, Kong L, Xiong L, Deng J, Barbera AJ, Zheng L, Zhang H, Huang S, Min J, Nicholson T, Chen T, Xu G, Shi Y, Zhang K, Shi YG.
Xu Y, et al.
Mol Cell. 2011 May 20;42(4):451-64. doi: 10.1016/j.molcel.2011.04.005. Epub 2011 Apr 21.
Mol Cell. 2011.
PMID: 21514197
Free PMC article.
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Human LSD2/KDM1b/AOF1 regulates gene transcription by modulating intragenic H3K4me2 methylation.
Fang R, Barbera AJ, Xu Y, Rutenberg M, Leonor T, Bi Q, Lan F, Mei P, Yuan GC, Lian C, Peng J, Cheng D, Sui G, Kaiser UB, Shi Y, Shi YG.
Fang R, et al.
Mol Cell. 2010 Jul 30;39(2):222-33. doi: 10.1016/j.molcel.2010.07.008.
Mol Cell. 2010.
PMID: 20670891
Free PMC article.
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