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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2007 1
2008 1
2009 2
2010 5
2011 4
2012 5
2013 1
2014 4
2015 4
2016 2
2019 1
2020 0
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25 results
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Page 1
A high-throughput chemical screen reveals that harmine-mediated inhibition of DYRK1A increases human pancreatic beta cell replication.
Wang P, Alvarez-Perez JC, Felsenfeld DP, Liu H, Sivendran S, Bender A, Kumar A, Sanchez R, Scott DK, Garcia-Ocaña A, Stewart AF. Wang P, et al. Nat Med. 2015 Apr;21(4):383-8. doi: 10.1038/nm.3820. Epub 2015 Mar 9. Nat Med. 2015. PMID: 25751815 Free PMC article.
Hypusine biosynthesis in β cells links polyamine metabolism to facultative cellular proliferation to maintain glucose homeostasis.
Levasseur EM, Yamada K, Piñeros AR, Wu W, Syed F, Orr KS, Anderson-Baucum E, Mastracci TL, Maier B, Mosley AL, Liu Y, Bernal-Mizrachi E, Alonso LC, Scott D, Garcia-Ocaña A, Tersey SA, Mirmira RG. Levasseur EM, et al. Sci Signal. 2019 Dec 3;12(610):eaax0715. doi: 10.1126/scisignal.aax0715. Sci Signal. 2019. PMID: 31796630 Free PMC article.
Diabetes mellitus--advances and challenges in human β-cell proliferation.
Wang P, Fiaschi-Taesch NM, Vasavada RC, Scott DK, García-Ocaña A, Stewart AF. Wang P, et al. Nat Rev Endocrinol. 2015 Apr;11(4):201-12. doi: 10.1038/nrendo.2015.9. Epub 2015 Feb 17. Nat Rev Endocrinol. 2015. PMID: 25687999 Review.
Human β-cell proliferation and intracellular signaling: part 3.
Stewart AF, Hussain MA, García-Ocaña A, Vasavada RC, Bhushan A, Bernal-Mizrachi E, Kulkarni RN. Stewart AF, et al. Diabetes. 2015 Jun;64(6):1872-85. doi: 10.2337/db14-1843. Diabetes. 2015. PMID: 25999530 Free PMC article. Review.
PKCζ Is Essential for Pancreatic β-Cell Replication During Insulin Resistance by Regulating mTOR and Cyclin-D2.
Lakshmipathi J, Alvarez-Perez JC, Rosselot C, Casinelli GP, Stamateris RE, Rausell-Palamos F, O'Donnell CP, Vasavada RC, Scott DK, Alonso LC, Garcia-Ocaña A. Lakshmipathi J, et al. Diabetes. 2016 May;65(5):1283-96. doi: 10.2337/db15-1398. Epub 2016 Feb 11. Diabetes. 2016. PMID: 26868297 Free PMC article.
Glucose Induces Mouse β-Cell Proliferation via IRS2, MTOR, and Cyclin D2 but Not the Insulin Receptor.
Stamateris RE, Sharma RB, Kong Y, Ebrahimpour P, Panday D, Ranganath P, Zou B, Levitt H, Parambil NA, O'Donnell CP, García-Ocaña A, Alonso LC. Stamateris RE, et al. Diabetes. 2016 Apr;65(4):981-95. doi: 10.2337/db15-0529. Epub 2016 Jan 6. Diabetes. 2016. PMID: 26740601 Free PMC article.
Phospho-BAD BH3 mimicry protects β cells and restores functional β cell mass in diabetes.
Ljubicic S, Polak K, Fu A, Wiwczar J, Szlyk B, Chang Y, Alvarez-Perez JC, Bird GH, Walensky LD, Garcia-Ocaña A, Danial NN. Ljubicic S, et al. Cell Rep. 2015 Feb 3;10(4):497-504. doi: 10.1016/j.celrep.2014.12.056. Epub 2015 Jan 29. Cell Rep. 2015. PMID: 25640178 Free PMC article.
Human β-cell proliferation and intracellular signaling part 2: still driving in the dark without a road map.
Bernal-Mizrachi E, Kulkarni RN, Scott DK, Mauvais-Jarvis F, Stewart AF, Garcia-Ocaña A. Bernal-Mizrachi E, et al. Diabetes. 2014 Mar;63(3):819-31. doi: 10.2337/db13-1146. Diabetes. 2014. PMID: 24556859 Free PMC article. Review.
ChREBP mediates glucose-stimulated pancreatic β-cell proliferation.
Metukuri MR, Zhang P, Basantani MK, Chin C, Stamateris RE, Alonso LC, Takane KK, Gramignoli R, Strom SC, O'Doherty RM, Stewart AF, Vasavada RC, Garcia-Ocaña A, Scott DK. Metukuri MR, et al. Diabetes. 2012 Aug;61(8):2004-15. doi: 10.2337/db11-0802. Epub 2012 May 14. Diabetes. 2012. PMID: 22586588 Free PMC article.
"RAS"ling β cells to proliferate for diabetes: why do we need MEN?
García-Ocaña A, Stewart AF. García-Ocaña A, et al. J Clin Invest. 2014 Sep;124(9):3698-700. doi: 10.1172/JCI77764. Epub 2014 Aug 18. J Clin Invest. 2014. PMID: 25133422 Free PMC article.
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