R01 DK091845/DK/NIDDK NIH HHS/United States[Grant Number] - Search Results

Year	Number of Results
2013	2
2015	2
2016	1
2018	3
2019	1
2021	1
2022	0

1

The Molecular Physiopathogenesis of Islet Amyloidosis.

Bhowmick DC, Singh S, Trikha S, Jeremic AM. Bhowmick DC, et al. Handb Exp Pharmacol. 2018;245:271-312. doi: 10.1007/164_2017_62. Handb Exp Pharmacol. 2018. PMID: 29043504 Free PMC article. Review.

2

Role of Cholesterol and Phospholipids in Amylin Misfolding, Aggregation and Etiology of Islet Amyloidosis.

Singh S, Trikha S, Bhowmick DC, Sarkar AA, Jeremic AM. Singh S, et al. Adv Exp Med Biol. 2015;855:95-116. doi: 10.1007/978-3-319-17344-3_4. Adv Exp Med Biol. 2015. PMID: 26149927 Free PMC article. Review.

3

An inducible model of human amylin overexpression reveals diverse transcriptional changes.

Aldras Y, Singh S, Bode K, Bhowmick DC, Jeremic A, O'Halloran DM. Aldras Y, et al. Neurosci Lett. 2019 Jun 21;704:212-219. doi: 10.1016/j.neulet.2019.04.016. Epub 2019 Apr 8. Neurosci Lett. 2019. PMID: 30974231 Free PMC article.

4

FoxA2 and RNA Pol II mediate human islet amyloid polypeptide turnover in ER-stressed pancreatic β-cells.

Chatterjee Bhowmick D, Burnett L, Kudaibergenova Z, Jeremic AM. Chatterjee Bhowmick D, et al. Biochem J. 2021 Mar 26;478(6):1261-1282. doi: 10.1042/BCJ20200984. Biochem J. 2021. PMID: 33650632 Free PMC article.

5

Proteasome regulates turnover of toxic human amylin in pancreatic cells.

Singh S, Trikha S, Sarkar A, Jeremic AM. Singh S, et al. Biochem J. 2016 Sep 1;473(17):2655-70. doi: 10.1042/BCJ20160026. Epub 2016 Jun 23. Biochem J. 2016. PMID: 27340132 Free PMC article.

6

Functional proteasome complex is required for turnover of islet amyloid polypeptide in pancreatic β-cells.

Chatterjee Bhowmick D, Jeremic A. Chatterjee Bhowmick D, et al. J Biol Chem. 2018 Sep 14;293(37):14210-14223. doi: 10.1074/jbc.RA118.002414. Epub 2018 Jul 16. J Biol Chem. 2018. PMID: 30012886 Free PMC article.

7

Copper(II)-human amylin complex protects pancreatic cells from amylin toxicity.

Lee EC, Ha E, Singh S, Legesse L, Ahmad S, Karnaukhova E, Donaldson RP, Jeremic AM. Lee EC, et al. Phys Chem Chem Phys. 2013 Aug 14;15(30):12558-71. doi: 10.1039/c3cp44542a. Phys Chem Chem Phys. 2013. PMID: 23793354 Free PMC article.

8

Apoptosis signal regulating kinase-1 and NADPH oxidase mediate human amylin evoked redox stress and apoptosis in pancreatic beta-cells.

Singh S, Bhowmick DC, Pany S, Joe M, Zaghlula N, Jeremic AM. Singh S, et al. Biochim Biophys Acta Biomembr. 2018 Sep;1860(9):1721-1733. doi: 10.1016/j.bbamem.2018.03.024. Epub 2018 Apr 6. Biochim Biophys Acta Biomembr. 2018. PMID: 29627323 Free PMC article.

9

Distinct internalization pathways of human amylin monomers and its cytotoxic oligomers in pancreatic cells.

Trikha S, Jeremic AM. Trikha S, et al. PLoS One. 2013 Sep 3;8(9):e73080. doi: 10.1371/journal.pone.0073080. eCollection 2013. PLoS One. 2013. PMID: 24019897 Free PMC article.

10

Rapid assessment of human amylin aggregation and its inhibition by copper(II) ions by laser ablation electrospray ionization mass spectrometry with ion mobility separation.

Li H, Ha E, Donaldson RP, Jeremic AM, Vertes A. Li H, et al. Anal Chem. 2015 Oct 6;87(19):9829-9837. doi: 10.1021/acs.analchem.5b02217. Anal Chem. 2015. PMID: 26352401 Free PMC article.

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