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Polymorphisms Associated With Metabolic Dysfunction-Associated Steatotic Liver Disease Influence the Progression of End-Stage Liver Disease.
Kocas-Kilicarslan ZN, Cetin Z, Faccioli LAP, Motomura T, Amirneni S, Diaz-Aragon R, Florentino RM, Sun Y, Pla-Palacin I, Xia M, Miedel MT, Kurihara T, Hu Z, Ostrowska A, Wang Z, Constantine R, Li A, Taylor DL, Behari J, Soto-Gutierrez A, Tafaleng EN. Kocas-Kilicarslan ZN, et al. Gastro Hep Adv. 2024;3(1):67-77. doi: 10.1016/j.gastha.2023.09.011. Epub 2023 Oct 5. Gastro Hep Adv. 2024. PMID: 38292457 Free PMC article.
VEGFA mRNA-LNP promotes biliary epithelial cell-to-hepatocyte conversion in acute and chronic liver diseases and reverses steatosis and fibrosis.
Rizvi F, Lee YR, Diaz-Aragon R, Bawa PS, So J, Florentino RM, Wu S, Sarjoo A, Truong E, Smith AR, Wang F, Everton E, Ostrowska A, Jung K, Tam Y, Muramatsu H, Pardi N, Weissman D, Soto-Gutierrez A, Shin D, Gouon-Evans V. Rizvi F, et al. Cell Stem Cell. 2023 Dec 7;30(12):1640-1657.e8. doi: 10.1016/j.stem.2023.10.008. Epub 2023 Nov 28. Cell Stem Cell. 2023. PMID: 38029740 Free article.
Evaluation of Human Hepatocyte Drug Metabolism Carrying High-Risk or Protection-Associated Liver Disease Genetic Variants.
Faccioli LAP, Cetin Z, Kocas-Kilicarslan ZN, Ortiz K, Sun Y, Hu Z, Kurihara T, Tafaleng EN, Florentino RM, Wang Z, Xia M, Miedel MT, Taylor DL, Behari J, Ostrowska A, Constantine R, Li A, Soto-Gutierrez A. Faccioli LAP, et al. Int J Mol Sci. 2023 Aug 29;24(17):13406. doi: 10.3390/ijms241713406. Int J Mol Sci. 2023. PMID: 37686209 Free PMC article.
Human Hepatocellular response in Cholestatic Liver Diseases.
Ortiz K, Cetin Z, Sun Y, Hu Z, Kurihara T, Tafaleng EN, Florentino RM, Ostrowska A, Soto-Gutierrez A, Faccioli LAP. Ortiz K, et al. Organogenesis. 2023 Dec 31;19(1):2247576. doi: 10.1080/15476278.2023.2247576. Organogenesis. 2023. PMID: 37598346 Free PMC article.
Biofabrication of synthetic human liver tissue with advanced programmable functions.
Florentino RM, Morita K, Haep N, Motomura T, Diaz-Aragon R, Faccioli LAP, Collin de l'Hortet A, Cetin Z, Frau C, Vernetti L, Amler AK, Thomas A, Lam T, Kloke L, Takeishi K, Taylor DL, Fox IJ, Soto-Gutierrez A. Florentino RM, et al. iScience. 2022 Nov 4;25(12):105503. doi: 10.1016/j.isci.2022.105503. eCollection 2022 Dec 22. iScience. 2022. PMID: 36404924 Free PMC article.
From a Single Cell to a Whole Human Liver: Disease Modeling and Transplantation.
Motomura T, Faccioli LAP, Diaz-Aragon R, Kocas-Kilicarslan ZN, Haep N, Florentino RM, Amirneni S, Cetin Z, Peri BS, Morita K, Ostrowska A, Takeishi K, Soto-Gutierrez A, Tafaleng EN. Motomura T, et al. Semin Liver Dis. 2022 Nov;42(4):413-422. doi: 10.1055/a-1934-5404. Epub 2022 Aug 31. Semin Liver Dis. 2022. PMID: 36044927 Free PMC article.
Transplantation of bioengineered liver capable of extended function in a preclinical liver failure model.
Higashi H, Yagi H, Kuroda K, Tajima K, Kojima H, Nishi K, Morisaku T, Hirukawa K, Fukuda K, Matsubara K, Kitago M, Shinoda M, Obara H, Adachi S, Nishimura K, Natsume T, Tomi M, Soto-Gutierrez A, Kitagawa Y. Higashi H, et al. Am J Transplant. 2022 Mar;22(3):731-744. doi: 10.1111/ajt.16928. Epub 2022 Jan 5. Am J Transplant. 2022. PMID: 34932270 Free PMC article.
Hepatocyte Nuclear Factor 4 alpha 2 Messenger RNA Reprograms Liver-Enriched Transcription Factors and Functional Proteins in End-Stage Cirrhotic Human Hepatocytes.
Tafaleng EN, Mukherjee A, Bell A, Morita K, Guzman-Lepe J, Haep N, Florentino RM, Diaz-Aragon R, Frau C, Ostrowska A, Schultz JR, Martini PGV, Soto-Gutierrez A, Fox IJ. Tafaleng EN, et al. Hepatol Commun. 2021 Nov;5(11):1911-1926. doi: 10.1002/hep4.1763. Epub 2021 Jul 1. Hepatol Commun. 2021. PMID: 34558820 Free PMC article.
27 results