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DACH1 protects podocytes from experimental diabetic injury and modulates PTIP-H3K4Me3 activity.
Cao A, Li J, Asadi M, Basgen JM, Zhu B, Yi Z, Jiang S, Doke T, El Shamy O, Patel N, Cravedi P, Azeloglu EU, Campbell KN, Menon M, Coca S, Zhang W, Wang H, Zen K, Liu Z, Murphy B, He JC, D'Agati VD, Susztak K, Kaufman L. Cao A, et al. J Clin Invest. 2021 May 17;131(10):e141279. doi: 10.1172/JCI141279. J Clin Invest. 2021. PMID: 33998601 Free PMC article.
Disruption of MAGI2-RapGEF2-Rap1 signaling contributes to podocyte dysfunction in congenital nephrotic syndrome caused by mutations in MAGI2.
Zhu B, Cao A, Li J, Young J, Wong J, Ashraf S, Bierzynska A, Menon MC, Hou S, Sawyers C, Campbell KN, Saleem MA, He JC, Hildebrandt F, D'Agati VD, Peng W, Kaufman L. Zhu B, et al. Kidney Int. 2019 Sep;96(3):642-655. doi: 10.1016/j.kint.2019.03.016. Epub 2019 Mar 28. Kidney Int. 2019. PMID: 31171376 Free PMC article.