R01 DK105550/DK/NIDDK NIH HHS/United States[Grant Number] - Search Results

Year	Number of Results
2015	3
2016	13
2017	5
2018	7
2019	5
2020	4
2021	0

1

A guide to immunometabolism for immunologists.

O'Neill LA, Kishton RJ, Rathmell J. O'Neill LA, et al. Nat Rev Immunol. 2016 Sep;16(9):553-65. doi: 10.1038/nri.2016.70. Epub 2016 Jul 11. Nat Rev Immunol. 2016. PMID: 27396447 Free PMC article. Review.

2

Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism.

Johnson MO, Wolf MM, Madden MZ, Andrejeva G, Sugiura A, Contreras DC, Maseda D, Liberti MV, Paz K, Kishton RJ, Johnson ME, de Cubas AA, Wu P, Li G, Zhang Y, Newcomb DC, Wells AD, Restifo NP, Rathmell WK, Locasale JW, Davila ML, Blazar BR, Rathmell JC. Johnson MO, et al. Cell. 2018 Dec 13;175(7):1780-1795.e19. doi: 10.1016/j.cell.2018.10.001. Epub 2018 Nov 1. Cell. 2018. PMID: 30392958 Free PMC article.

3

Targeting Metabolism to Improve the Tumor Microenvironment for Cancer Immunotherapy.

Bader JE, Voss K, Rathmell JC. Bader JE, et al. Mol Cell. 2020 Jun 18;78(6):1019-1033. doi: 10.1016/j.molcel.2020.05.034. Mol Cell. 2020. PMID: 32559423 Review.

4

Similarities and Distinctions of Cancer and Immune Metabolism in Inflammation and Tumors.

Andrejeva G, Rathmell JC. Andrejeva G, et al. Cell Metab. 2017 Jul 5;26(1):49-70. doi: 10.1016/j.cmet.2017.06.004. Cell Metab. 2017. PMID: 28683294 Free PMC article.

5

T cell metabolic fitness in antitumor immunity.

Siska PJ, Rathmell JC. Siska PJ, et al. Trends Immunol. 2015 Apr;36(4):257-64. doi: 10.1016/j.it.2015.02.007. Epub 2015 Mar 12. Trends Immunol. 2015. PMID: 25773310 Free PMC article. Review.

6

Efferocytosis induces a novel SLC program to promote glucose uptake and lactate release.

Morioka S, Perry JSA, Raymond MH, Medina CB, Zhu Y, Zhao L, Serbulea V, Onengut-Gumuscu S, Leitinger N, Kucenas S, Rathmell JC, Makowski L, Ravichandran KS. Morioka S, et al. Nature. 2018 Nov;563(7733):714-718. doi: 10.1038/s41586-018-0735-5. Epub 2018 Nov 21. Nature. 2018. PMID: 30464343 Free PMC article.

7

The Transcription Factor Bhlhe40 Programs Mitochondrial Regulation of Resident CD8⁺ T Cell Fitness and Functionality.

Li C, Zhu B, Son YM, Wang Z, Jiang L, Xiang M, Ye Z, Beckermann KE, Wu Y, Jenkins JW, Siska PJ, Vincent BG, Prakash YS, Peikert T, Edelson BT, Taneja R, Kaplan MH, Rathmell JC, Dong H, Hitosugi T, Sun J. Li C, et al. Immunity. 2019 Sep 17;51(3):491-507.e7. doi: 10.1016/j.immuni.2019.08.013. Immunity. 2019. PMID: 31533057 Free PMC article.

8

Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models.

Schulte ML, Fu A, Zhao P, Li J, Geng L, Smith ST, Kondo J, Coffey RJ, Johnson MO, Rathmell JC, Sharick JT, Skala MC, Smith JA, Berlin J, Washington MK, Nickels ML, Manning HC. Schulte ML, et al. Nat Med. 2018 Feb;24(2):194-202. doi: 10.1038/nm.4464. Epub 2018 Jan 15. Nat Med. 2018. PMID: 29334372 Free PMC article.

9

Differential glucose requirement in skin homeostasis and injury identifies a therapeutic target for psoriasis.

Zhang Z, Zi Z, Lee EE, Zhao J, Contreras DC, South AP, Abel ED, Chong BF, Vandergriff T, Hosler GA, Scherer PE, Mettlen M, Rathmell JC, DeBerardinis RJ, Wang RC. Zhang Z, et al. Nat Med. 2018 May;24(5):617-627. doi: 10.1038/s41591-018-0003-0. Epub 2018 Apr 16. Nat Med. 2018. PMID: 29662201 Free PMC article.

10

Foxp3 and Toll-like receptor signaling balance T_reg cell anabolic metabolism for suppression.

Gerriets VA, Kishton RJ, Johnson MO, Cohen S, Siska PJ, Nichols AG, Warmoes MO, de Cubas AA, MacIver NJ, Locasale JW, Turka LA, Wells AD, Rathmell JC. Gerriets VA, et al. Nat Immunol. 2016 Dec;17(12):1459-1466. doi: 10.1038/ni.3577. Epub 2016 Oct 3. Nat Immunol. 2016. PMID: 27695003 Free PMC article.

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