R01 DK54736/DK/NIDDK NIH HHS/United States[Grant Number] - Search Results

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Year	Number of Results
2000	2
2001	1
2004	2
2005	2
2022	0

Page 1

The structure and function of the Niemann-Pick C1 protein.

Ioannou YA. Ioannou YA. Mol Genet Metab. 2000 Sep-Oct;71(1-2):175-81. doi: 10.1006/mgme.2000.3061. Mol Genet Metab. 2000. PMID: 11001808 Review.

The NPC1 protein: structure implies function.

Scott C, Ioannou YA. Scott C, et al. Biochim Biophys Acta. 2004 Oct 11;1685(1-3):8-13. doi: 10.1016/j.bbalip.2004.08.006. Biochim Biophys Acta. 2004. PMID: 15465421 Review.

Transmembrane molecular pump activity of Niemann-Pick C1 protein.

Davies JP, Chen FW, Ioannou YA. Davies JP, et al. Science. 2000 Dec 22;290(5500):2295-8. doi: 10.1126/science.290.5500.2295. Science. 2000. PMID: 11125140

Inactivation of NPC1L1 causes multiple lipid transport defects and protects against diet-induced hypercholesterolemia.

Davies JP, Scott C, Oishi K, Liapis A, Ioannou YA. Davies JP, et al. J Biol Chem. 2005 Apr 1;280(13):12710-20. doi: 10.1074/jbc.M409110200. Epub 2005 Jan 25. J Biol Chem. 2005. PMID: 15671032 Free article.

Targeting of NPC1 to late endosomes involves multiple signals, including one residing within the putative sterol-sensing domain.

Scott C, Higgins ME, Davies JP, Ioannou YA. Scott C, et al. J Biol Chem. 2004 Nov 12;279(46):48214-23. doi: 10.1074/jbc.M406090200. Epub 2004 Sep 3. J Biol Chem. 2004. PMID: 15347664 Free article.

NPC1 late endosomes contain elevated levels of non-esterified ('free') fatty acids and an abnormally glycosylated form of the NPC2 protein.

Chen FW, Gordon RE, Ioannou YA. Chen FW, et al. Biochem J. 2005 Sep 1;390(Pt 2):549-61. doi: 10.1042/BJ20050236. Biochem J. 2005. PMID: 15896196 Free PMC article.

Apoptosis-induced release of mature sterol regulatory element-binding proteins activates sterol-responsive genes.

Higgins ME, Ioannou YA. Higgins ME, et al. J Lipid Res. 2001 Dec;42(12):1939-46. J Lipid Res. 2001. PMID: 11734566 Free article.

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