Although sensory processing in V1 has been extensively characterized, the role of GABAergic inhibition is still not well understood. Advances in molecular biology have now removed significant barriers to the direct investigation of inhibitory processes in vivo. Recent studies have provided important insights into the influence of GABAergic inhibition on cortical processing at both the single cell level, where inhibition helps to shape cortical receptive fields, and at the network level, where inhibition is critical for generating cortical oscillations and setting network state.
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