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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1995 2
1996 5
1997 10
1998 2
1999 5
2000 6
2001 3
2002 8
2003 9
2004 9
2005 4
2006 4
2007 6
2008 4
2009 9
2010 10
2011 17
2012 16
2013 14
2022 0
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134 results
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Page 1
PKM2 isoform-specific deletion reveals a differential requirement for pyruvate kinase in tumor cells.
Israelsen WJ, Dayton TL, Davidson SM, Fiske BP, Hosios AM, Bellinger G, Li J, Yu Y, Sasaki M, Horner JW, Burga LN, Xie J, Jurczak MJ, DePinho RA, Clish CB, Jacks T, Kibbey RG, Wulf GM, Di Vizio D, Mills GB, Cantley LC, Vander Heiden MG. Israelsen WJ, et al. Cell. 2013 Oct 10;155(2):397-409. doi: 10.1016/j.cell.2013.09.025. Cell. 2013. PMID: 24120138 Free PMC article.
Metformin decreases glucose oxidation and increases the dependency of prostate cancer cells on reductive glutamine metabolism.
Fendt SM, Bell EL, Keibler MA, Davidson SM, Wirth GJ, Fiske B, Mayers JR, Schwab M, Bellinger G, Csibi A, Patnaik A, Blouin MJ, Cantley LC, Guarente L, Blenis J, Pollak MN, Olumi AF, Vander Heiden MG, Stephanopoulos G. Fendt SM, et al. Cancer Res. 2013 Jul 15;73(14):4429-38. doi: 10.1158/0008-5472.CAN-13-0080. Epub 2013 May 17. Cancer Res. 2013. PMID: 23687346 Free PMC article.
Protein tyrosine phosphatase 1B regulates pyruvate kinase M2 tyrosine phosphorylation.
Bettaieb A, Bakke J, Nagata N, Matsuo K, Xi Y, Liu S, AbouBechara D, Melhem R, Stanhope K, Cummings B, Graham J, Bremer A, Zhang S, Lyssiotis CA, Zhang ZY, Cantley LC, Havel PJ, Haj FG. Bettaieb A, et al. J Biol Chem. 2013 Jun 14;288(24):17360-71. doi: 10.1074/jbc.M112.441469. Epub 2013 May 2. J Biol Chem. 2013. PMID: 23640882 Free PMC article.
Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway.
Son J, Lyssiotis CA, Ying H, Wang X, Hua S, Ligorio M, Perera RM, Ferrone CR, Mullarky E, Shyh-Chang N, Kang Y, Fleming JB, Bardeesy N, Asara JM, Haigis MC, DePinho RA, Cantley LC, Kimmelman AC. Son J, et al. Nature. 2013 Apr 4;496(7443):101-5. doi: 10.1038/nature12040. Epub 2013 Mar 27. Nature. 2013. PMID: 23535601 Free PMC article.
Cancer metabolism: fatty acid oxidation in the limelight.
Carracedo A, Cantley LC, Pandolfi PP. Carracedo A, et al. Nat Rev Cancer. 2013 Apr;13(4):227-32. doi: 10.1038/nrc3483. Epub 2013 Feb 28. Nat Rev Cancer. 2013. PMID: 23446547 Free PMC article. Review.
134 results