R01 GM058600/GM/NIGMS NIH HHS/United States[Grant Number] - Search Results

Year	Number of Results
2007	1
2008	1
2009	1
2010	2
2011	3
2012	5
2013	2
2014	2
2015	1
2016	3
2017	3
2018	2
2019	1
2020	1
2021	0

1

Breaking up and making up: The secret life of the vacuolar H⁺ -ATPase.

Oot RA, Couoh-Cardel S, Sharma S, Stam NJ, Wilkens S. Oot RA, et al. Protein Sci. 2017 May;26(5):896-909. doi: 10.1002/pro.3147. Epub 2017 Mar 16. Protein Sci. 2017. PMID: 28247968 Free PMC article. Review.

2

Cryo-EM and MD infer water-mediated proton transport and autoinhibition mechanisms of V_o complex.

Roh SH, Shekhar M, Pintilie G, Chipot C, Wilkens S, Singharoy A, Chiu W. Roh SH, et al. Sci Adv. 2020 Oct 7;6(41):eabb9605. doi: 10.1126/sciadv.abb9605. Print 2020 Oct. Sci Adv. 2020. PMID: 33028525 Free PMC article.

3

Functional reconstitution of vacuolar H⁺-ATPase from V_o proton channel and mutant V₁-ATPase provides insight into the mechanism of reversible disassembly.

Sharma S, Oot RA, Khan MM, Wilkens S. Sharma S, et al. J Biol Chem. 2019 Apr 19;294(16):6439-6449. doi: 10.1074/jbc.RA119.007577. Epub 2019 Feb 21. J Biol Chem. 2019. PMID: 30792311 Free PMC article.

4

Biolayer interferometry of lipid nanodisc-reconstituted yeast vacuolar H⁺ -ATPase.

Sharma S, Wilkens S. Sharma S, et al. Protein Sci. 2017 May;26(5):1070-1079. doi: 10.1002/pro.3143. Epub 2017 Mar 12. Protein Sci. 2017. PMID: 28241399 Free PMC article.

5

Crystal structure of yeast V1-ATPase in the autoinhibited state.

Oot RA, Kane PM, Berry EA, Wilkens S. Oot RA, et al. EMBO J. 2016 Aug 1;35(15):1694-706. doi: 10.15252/embj.201593447. Epub 2016 Jun 13. EMBO J. 2016. PMID: 27295975 Free PMC article.

6

The 3.5-Å CryoEM Structure of Nanodisc-Reconstituted Yeast Vacuolar ATPase V_o Proton Channel.

Roh SH, Stam NJ, Hryc CF, Couoh-Cardel S, Pintilie G, Chiu W, Wilkens S. Roh SH, et al. Mol Cell. 2018 Mar 15;69(6):993-1004.e3. doi: 10.1016/j.molcel.2018.02.006. Epub 2018 Mar 8. Mol Cell. 2018. PMID: 29526695 Free PMC article.

7

Structure of dimeric F1F0-ATP synthase.

Couoh-Cardel SJ, Uribe-Carvajal S, Wilkens S, García-Trejo JJ. Couoh-Cardel SJ, et al. J Biol Chem. 2010 Nov 19;285(47):36447-55. doi: 10.1074/jbc.M110.144907. Epub 2010 Sep 10. J Biol Chem. 2010. PMID: 20833715 Free PMC article.

8

MgATP hydrolysis destabilizes the interaction between subunit H and yeast V₁-ATPase, highlighting H's role in V-ATPase regulation by reversible disassembly.

Sharma S, Oot RA, Wilkens S. Sharma S, et al. J Biol Chem. 2018 Jul 6;293(27):10718-10730. doi: 10.1074/jbc.RA118.002951. Epub 2018 May 12. J Biol Chem. 2018. PMID: 29754144 Free PMC article.

9

Yeast V-ATPase Proteolipid Ring Acts as a Large-conductance Transmembrane Protein Pore.

Couoh-Cardel S, Hsueh YC, Wilkens S, Movileanu L. Couoh-Cardel S, et al. Sci Rep. 2016 Apr 21;6:24774. doi: 10.1038/srep24774. Sci Rep. 2016. PMID: 27098228 Free PMC article.

10

On the origin of large flexibility of P-glycoprotein in the inward-facing state.

Wen PC, Verhalen B, Wilkens S, Mchaourab HS, Tajkhorshid E. Wen PC, et al. J Biol Chem. 2013 Jun 28;288(26):19211-20. doi: 10.1074/jbc.M113.450114. Epub 2013 May 8. J Biol Chem. 2013. PMID: 23658020 Free PMC article.

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