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Effect of the beta-glucuronidase inhibitor saccharolactone on glucuronidation by human tissue microsomes and recombinant UDP-glucuronosyltransferases.
J Pharm Pharmacol. 2008 Sep;60(9):1175-82. doi: 10.1211/jpp.60.9.0009.
J Pharm Pharmacol. 2008.
PMID: 18718121
Free PMC article.
Curcuminoids inhibit multiple human cytochromes P450, UDP-glucuronosyltransferase, and sulfotransferase enzymes, whereas piperine is a relatively selective CYP3A4 inhibitor.
Volak LP, Ghirmai S, Cashman JR, Court MH.
Volak LP, et al.
Drug Metab Dispos. 2008 Aug;36(8):1594-605. doi: 10.1124/dmd.108.020552. Epub 2008 May 14.
Drug Metab Dispos. 2008.
PMID: 18480186
Free PMC article.
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