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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2007 5
2008 1
2009 2
2010 4
2020 0
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12 results
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Page 1
Engineering enzymes by 'intelligent' design.
Kazlauskas R, Lutz S. Kazlauskas R, et al. Curr Opin Chem Biol. 2009 Feb;13(1):1-2. doi: 10.1016/j.cbpa.2009.02.022. Epub 2009 Mar 9. Curr Opin Chem Biol. 2009. PMID: 19272831 Free PMC article. No abstract available.
Beyond directed evolution--semi-rational protein engineering and design.
Lutz S. Lutz S. Curr Opin Biotechnol. 2010 Dec;21(6):734-43. doi: 10.1016/j.copbio.2010.08.011. Epub 2010 Sep 24. Curr Opin Biotechnol. 2010. PMID: 20869867 Free PMC article. Review.
Biochemistry. Reengineering enzymes.
Lutz S. Lutz S. Science. 2010 Jul 16;329(5989):285-7. doi: 10.1126/science.1192224. Science. 2010. PMID: 20647454 Free PMC article. No abstract available.
Computational design of orthogonal nucleoside kinases.
Liu L, Murphy P, Baker D, Lutz S. Liu L, et al. Chem Commun (Camb). 2010 Dec 14;46(46):8803-5. doi: 10.1039/c0cc02961k. Epub 2010 Oct 19. Chem Commun (Camb). 2010. PMID: 20959903 Free PMC article.
Engineering Kinases to Phosphorylate Nucleoside Analogs for Antiviral and Cancer Therapy.
Lutz S, Liu L, Liu Y. Lutz S, et al. Chimia (Aarau). 2009 Nov 1;63(11):737-744. doi: 10.2533/chimia.2009.737. Chimia (Aarau). 2009. PMID: 20305804 Free PMC article.
Binding of ATP to TK1-like enzymes is associated with a conformational change in the quaternary structure.
Segura-Peña D, Lutz S, Monnerjahn C, Konrad M, Lavie A. Segura-Peña D, et al. J Mol Biol. 2007 May 25;369(1):129-41. doi: 10.1016/j.jmb.2007.02.104. Epub 2007 Mar 15. J Mol Biol. 2007. PMID: 17407781 Free PMC article.
Exploiting temperature-dependent substrate promiscuity for nucleoside analogue activation by thymidine kinase from Thermotoga maritima.
Lutz S, Lichter J, Liu L. Lutz S, et al. J Am Chem Soc. 2007 Jul 18;129(28):8714-5. doi: 10.1021/ja0734391. Epub 2007 Jun 26. J Am Chem Soc. 2007. PMID: 17592850 Free PMC article.
Quaternary structure change as a mechanism for the regulation of thymidine kinase 1-like enzymes.
Segura-Peña D, Lichter J, Trani M, Konrad M, Lavie A, Lutz S. Segura-Peña D, et al. Structure. 2007 Dec;15(12):1555-66. doi: 10.1016/j.str.2007.09.025. Structure. 2007. PMID: 18073106 Free PMC article.
Non-homologous recombination of deoxyribonucleoside kinases from human and Drosophila melanogaster yields human-like enzymes with novel activities.
Gerth ML, Lutz S. Gerth ML, et al. J Mol Biol. 2007 Jul 20;370(4):742-51. doi: 10.1016/j.jmb.2007.05.021. Epub 2007 May 22. J Mol Biol. 2007. PMID: 17543337 Free PMC article.
Synthesis of fluorescent nucleoside analogs as probes for 2'-deoxyribonucleoside kinases.
Li Y, Soni PB, Liu L, Zhang X, Liotta DC, Lutz S. Li Y, et al. Bioorg Med Chem Lett. 2010 Feb 1;20(3):841-3. doi: 10.1016/j.bmcl.2009.12.097. Epub 2010 Jan 4. Bioorg Med Chem Lett. 2010. PMID: 20060716 Free PMC article.
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