R01 GM090324/GM/NIGMS NIH HHS/United States[Grant Number] - Search Results

Year	Number of Results
2009	3
2010	1
2011	2
2012	4
2013	3
2014	1
2015	2
2016	2
2017	4
2019	2
2021	0

1

Inhibition of RAS function through targeting an allosteric regulatory site.

Spencer-Smith R, Koide A, Zhou Y, Eguchi RR, Sha F, Gajwani P, Santana D, Gupta A, Jacobs M, Herrero-Garcia E, Cobbert J, Lavoie H, Smith M, Rajakulendran T, Dowdell E, Okur MN, Dementieva I, Sicheri F, Therrien M, Hancock JF, Ikura M, Koide S, O'Bryan JP. Spencer-Smith R, et al. Nat Chem Biol. 2017 Jan;13(1):62-68. doi: 10.1038/nchembio.2231. Epub 2016 Nov 7. Nat Chem Biol. 2017. PMID: 27820802 Free PMC article.

2

Allosteric modulation of a human protein kinase with monobodies.

Zorba A, Nguyen V, Koide A, Hoemberger M, Zheng Y, Kutter S, Kim C, Koide S, Kern D. Zorba A, et al. Proc Natl Acad Sci U S A. 2019 Jul 9;116(28):13937-13942. doi: 10.1073/pnas.1906024116. Epub 2019 Jun 25. Proc Natl Acad Sci U S A. 2019. PMID: 31239342 Free PMC article.

3

Structural insights for engineering binding proteins based on non-antibody scaffolds.

Gilbreth RN, Koide S. Gilbreth RN, et al. Curr Opin Struct Biol. 2012 Aug;22(4):413-20. doi: 10.1016/j.sbi.2012.06.001. Epub 2012 Jun 27. Curr Opin Struct Biol. 2012. PMID: 22749196 Free PMC article. Review.

4

Architecture of the fungal nuclear pore inner ring complex.

Stuwe T, Bley CJ, Thierbach K, Petrovic S, Schilbach S, Mayo DJ, Perriches T, Rundlet EJ, Jeon YE, Collins LN, Huber FM, Lin DH, Paduch M, Koide A, Lu V, Fischer J, Hurt E, Koide S, Kossiakoff AA, Hoelz A. Stuwe T, et al. Science. 2015 Oct 2;350(6256):56-64. doi: 10.1126/science.aac9176. Epub 2015 Aug 27. Science. 2015. PMID: 26316600 Free PMC article.

5

Targeting the α4-α5 interface of RAS results in multiple levels of inhibition.

Spencer-Smith R, Li L, Prasad S, Koide A, Koide S, O'Bryan JP. Spencer-Smith R, et al. Small GTPases. 2019 Sep;10(5):378-387. doi: 10.1080/21541248.2017.1333188. Epub 2017 Dec 31. Small GTPases. 2019. PMID: 28692342 Free PMC article.

6

Structural and functional dissection of the DH and PH domains of oncogenic Bcr-Abl tyrosine kinase.

Reckel S, Gehin C, Tardivon D, Georgeon S, Kükenshöner T, Löhr F, Koide A, Buchner L, Panjkovich A, Reynaud A, Pinho S, Gerig B, Svergun D, Pojer F, Güntert P, Dötsch V, Koide S, Gavin AC, Hantschel O. Reckel S, et al. Nat Commun. 2017 Dec 13;8(1):2101. doi: 10.1038/s41467-017-02313-6. Nat Commun. 2017. PMID: 29235475 Free PMC article.

7

Affinity maturation of single-domain antibodies by yeast surface display.

Koide A, Koide S. Koide A, et al. Methods Mol Biol. 2012;911:431-43. doi: 10.1007/978-1-61779-968-6_26. Methods Mol Biol. 2012. PMID: 22886267

8

Selective Targeting of SH2 Domain-Phosphotyrosine Interactions of Src Family Tyrosine Kinases with Monobodies.

Kükenshöner T, Schmit NE, Bouda E, Sha F, Pojer F, Koide A, Seeliger M, Koide S, Hantschel O. Kükenshöner T, et al. J Mol Biol. 2017 May 5;429(9):1364-1380. doi: 10.1016/j.jmb.2017.03.023. Epub 2017 Mar 25. J Mol Biol. 2017. PMID: 28347651 Free PMC article.

9

Structures of a Na+-coupled, substrate-bound MATE multidrug transporter.

Lu M, Symersky J, Radchenko M, Koide A, Guo Y, Nie R, Koide S. Lu M, et al. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):2099-104. doi: 10.1073/pnas.1219901110. Epub 2013 Jan 22. Proc Natl Acad Sci U S A. 2013. PMID: 23341609 Free PMC article.

10

Directed network wiring identifies a key protein interaction in embryonic stem cell differentiation.

Yasui N, Findlay GM, Gish GD, Hsiung MS, Huang J, Tucholska M, Taylor L, Smith L, Boldridge WC, Koide A, Pawson T, Koide S. Yasui N, et al. Mol Cell. 2014 Jun 19;54(6):1034-41. doi: 10.1016/j.molcel.2014.05.002. Epub 2014 Jun 5. Mol Cell. 2014. PMID: 24910098 Free PMC article.

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