R01 GM105671/GM/NIGMS NIH HHS/United States[Grant Number] - Search Results

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Subject: R01 GM105671/GM/NIGMS NIH HHS/United States[Grant - PubMed

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Results by year

Year	Number of Results
2013	1
2014	4
2015	2
2016	3
2017	9
2018	8
2019	3
2020	5
2021	7
2022	2
2024	0

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Supplementation with omega-3 or omega-6 fatty acids attenuates platelet reactivity in postmenopausal women.

Yamaguchi A, Stanger L, Freedman JC, Prieur A, Thav R, Tena J, Holman TR, Holinstat M. Yamaguchi A, et al. Clin Transl Sci. 2022 Oct;15(10):2378-2391. doi: 10.1111/cts.13366. Epub 2022 Jul 25. Clin Transl Sci. 2022. PMID: 35791734 Free PMC article.

Structural basis for altered positional specificity of 15-lipoxygenase-1 with 5S-HETE and 7S-HDHA and the implications for the biosynthesis of resolvin E4.

Perry SC, van Hoorebeke C, Sorrentino J, Bautista L, Akinkugbe O, Conrad WS, Rutz N, Holman TR. Perry SC, et al. Arch Biochem Biophys. 2022 Sep 30;727:109317. doi: 10.1016/j.abb.2022.109317. Epub 2022 Jun 13. Arch Biochem Biophys. 2022. PMID: 35709965

Kinetic and structural investigations of novel inhibitors of human epithelial 15-lipoxygenase-2.

Tsai WC, Gilbert NC, Ohler A, Armstrong M, Perry S, Kalyanaraman C, Yasgar A, Rai G, Simeonov A, Jadhav A, Standley M, Lee HW, Crews P, Iavarone AT, Jacobson MP, Neau DB, Offenbacher AR, Newcomer M, Holman TR. Tsai WC, et al. Bioorg Med Chem. 2021 Sep 15;46:116349. doi: 10.1016/j.bmc.2021.116349. Epub 2021 Aug 5. Bioorg Med Chem. 2021. PMID: 34500187 Free PMC article.

Pharmacologic targeting of Cdc42 GTPase by a small molecule Cdc42 activity-specific inhibitor prevents platelet activation and thrombosis.

Duan X, Perveen R, Dandamudi A, Adili R, Johnson J, Funk K, Berryman M, Davis AK, Holinstat M, Zheng Y, Akbar H. Duan X, et al. Sci Rep. 2021 Jun 23;11(1):13170. doi: 10.1038/s41598-021-92654-6. Sci Rep. 2021. PMID: 34162972 Free PMC article.

Slounase, a Batroxobin Containing Activated Factor X Effectively Enhances Hemostatic Clot Formation and Reducing Bleeding in Hypocoagulant Conditions in Mice.

Adili R, Jackson M, Stanger L, Dai X, Li M, Li BX, Holinstat M. Adili R, et al. Clin Appl Thromb Hemost. 2021 Jan-Dec;27:10760296211018510. doi: 10.1177/10760296211018510. Clin Appl Thromb Hemost. 2021. PMID: 34047195 Free PMC article.

In Vitro Biosynthetic Pathway Investigations of Neuroprotectin D1 (NPD1) and Protectin DX (PDX) by Human 12-Lipoxygenase, 15-Lipoxygenase-1, and 15-Lipoxygenase-2.

Tsai WC, Kalyanaraman C, Yamaguchi A, Holinstat M, Jacobson MP, Holman TR. Tsai WC, et al. Biochemistry. 2021 Jun 8;60(22):1741-1754. doi: 10.1021/acs.biochem.0c00931. Epub 2021 May 24. Biochemistry. 2021. PMID: 34029049 Free PMC article.

Deformable microparticles for shuttling nanoparticles to the vascular wall.

Fish MB, Banka AL, Braunreuther M, Fromen CA, Kelley WJ, Lee J, Adili R, Holinstat M, Eniola-Adefeso O. Fish MB, et al. Sci Adv. 2021 Apr 21;7(17):eabe0143. doi: 10.1126/sciadv.abe0143. Print 2021 Apr. Sci Adv. 2021. PMID: 33883129 Free PMC article.

Antisense oligonucleotides and nucleic acids generate hypersensitive platelets.

Zaslavsky A, Adams M, Cao X, Yamaguchi A, Henderson J, Busch-Østergren P, Udager A, Pitchiaya S, Tourdot B, Kasputis T, Church SJ, Lee SK, Ohl S, Patel S, Morgan TM, Alva A, Wakefield TW, Reichert Z, Holinstat M, Palapattu GS. Zaslavsky A, et al. Thromb Res. 2021 Apr;200:64-71. doi: 10.1016/j.thromres.2021.01.006. Epub 2021 Jan 18. Thromb Res. 2021. PMID: 33540294 Free PMC article.

DHA 12-LOX-derived oxylipins regulate platelet activation and thrombus formation through a PKA-dependent signaling pathway.

Yamaguchi A, Stanger L, Freedman CJ, Standley M, Hoang T, Adili R, Tsai WC, van Hoorebeke C, Holman TR, Holinstat M. Yamaguchi A, et al. J Thromb Haemost. 2021 Mar;19(3):839-851. doi: 10.1111/jth.15184. Epub 2020 Dec 16. J Thromb Haemost. 2021. PMID: 33222370 Free PMC article.

Role of Human 15-Lipoxygenase-2 in the Biosynthesis of the Lipoxin Intermediate, 5S,15S-diHpETE, Implicated with the Altered Positional Specificity of Human 15-Lipoxygenase-1.

Perry SC, Horn T, Tourdot BE, Yamaguchi A, Kalyanaraman C, Conrad WS, Akinkugbe O, Holinstat M, Jacobson MP, Holman TR. Perry SC, et al. Biochemistry. 2020 Oct 27;59(42):4118-4130. doi: 10.1021/acs.biochem.0c00622. Epub 2020 Oct 13. Biochemistry. 2020. PMID: 33048542 Free PMC article.

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