R01 GM111955/GM/NIGMS NIH HHS/United States[Grant Number] - Search Results

Year	Number of Results
2014	1
2015	1
2016	5
2017	1
2018	1
2022	0

1

Structure-Based Prediction of Protein-Folding Transition Paths.

Jacobs WM, Shakhnovich EI. Jacobs WM, et al. Biophys J. 2016 Sep 6;111(5):925-36. doi: 10.1016/j.bpj.2016.06.031. Biophys J. 2016. PMID: 27602721 Free PMC article.

2

Bridging the physical scales in evolutionary biology: from protein sequence space to fitness of organisms and populations.

Bershtein S, Serohijos AW, Shakhnovich EI. Bershtein S, et al. Curr Opin Struct Biol. 2017 Feb;42:31-40. doi: 10.1016/j.sbi.2016.10.013. Epub 2016 Oct 31. Curr Opin Struct Biol. 2017. PMID: 27810574 Free PMC article. Review.

3

Transient protein-protein interactions perturb E. coli metabolome and cause gene dosage toxicity.

Bhattacharyya S, Bershtein S, Yan J, Argun T, Gilson AI, Trauger SA, Shakhnovich EI. Bhattacharyya S, et al. Elife. 2016 Dec 10;5:e20309. doi: 10.7554/eLife.20309. Elife. 2016. PMID: 27938662 Free PMC article.

4

Dynamic disulfide exchange in a crystallin protein in the human eye lens promotes cataract-associated aggregation.

Serebryany E, Yu S, Trauger SA, Budnik B, Shakhnovich EI. Serebryany E, et al. J Biol Chem. 2018 Nov 16;293(46):17997-18009. doi: 10.1074/jbc.RA118.004551. Epub 2018 Sep 21. J Biol Chem. 2018. PMID: 30242128 Free PMC article.

5

An Internal Disulfide Locks a Misfolded Aggregation-prone Intermediate in Cataract-linked Mutants of Human γD-Crystallin.

Serebryany E, Woodard JC, Adkar BV, Shabab M, King JA, Shakhnovich EI. Serebryany E, et al. J Biol Chem. 2016 Sep 2;291(36):19172-83. doi: 10.1074/jbc.M116.735977. Epub 2016 Jul 14. J Biol Chem. 2016. PMID: 27417136 Free PMC article.

6

Gene Dosage Experiments in Enterobacteriaceae Using Arabinose-regulated Promoters.

Bhattacharyya S, Bershtein S, Shakhnovich EI. Bhattacharyya S, et al. Bio Protoc. 2014 Jul 20;7(14):e2396. doi: 10.21769/BioProtoc.2396. Bio Protoc. 2014. PMID: 29170750 Free PMC article.

7

A Simple Model of Protein Domain Swapping in Crowded Cellular Environments.

Woodard JC, Dunatunga S, Shakhnovich EI. Woodard JC, et al. Biophys J. 2016 Jun 7;110(11):2367-2376. doi: 10.1016/j.bpj.2016.04.033. Biophys J. 2016. PMID: 27276255 Free PMC article.

8

Is catalytic activity of chaperones a selectable trait for the emergence of heat shock response?

Çetinbaş M, Shakhnovich EI. Çetinbaş M, et al. Biophys J. 2015 Jan 20;108(2):438-48. doi: 10.1016/j.bpj.2014.11.3468. Biophys J. 2015. PMID: 25606691 Free PMC article.

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