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Page 1
Metabolic Maturation Media Improve Physiological Function of Human iPSC-Derived Cardiomyocytes.
Feyen DAM, McKeithan WL, Bruyneel AAN, Spiering S, Hörmann L, Ulmer B, Zhang H, Briganti F, Schweizer M, Hegyi B, Liao Z, Pölönen RP, Ginsburg KS, Lam CK, Serrano R, Wahlquist C, Kreymerman A, Vu M, Amatya PL, Behrens CS, Ranjbarvaziri S, Maas RGC, Greenhaw M, Bernstein D, Wu JC, Bers DM, Eschenhagen T, Metallo CM, Mercola M. Feyen DAM, et al. Cell Rep. 2020 Jul 21;32(3):107925. doi: 10.1016/j.celrep.2020.107925. Cell Rep. 2020. PMID: 32697997 Free PMC article.
Serine biosynthesis as a novel therapeutic target for dilated cardiomyopathy.
Perea-Gil I, Seeger T, Bruyneel AAN, Termglinchan V, Monte E, Lim EW, Vadgama N, Furihata T, Gavidia AA, Arthur Ataam J, Bharucha N, Martinez-Amador N, Ameen M, Nair P, Serrano R, Kaur B, Feyen DAM, Diecke S, Snyder MP, Metallo CM, Mercola M, Karakikes I. Perea-Gil I, et al. Eur Heart J. 2022 Sep 21;43(36):3477-3489. doi: 10.1093/eurheartj/ehac305. Eur Heart J. 2022. PMID: 35728000 Free PMC article.
Human iPSC modeling of heart disease for drug development.
Hnatiuk AP, Briganti F, Staudt DW, Mercola M. Hnatiuk AP, et al. Cell Chem Biol. 2021 Mar 18;28(3):271-282. doi: 10.1016/j.chembiol.2021.02.016. Cell Chem Biol. 2021. PMID: 33740432 Free PMC article. Review.
A deep learning platform to assess drug proarrhythmia risk.
Serrano R, Feyen DAM, Bruyneel AAN, Hnatiuk AP, Vu MM, Amatya PL, Perea-Gil I, Prado M, Seeger T, Wu JC, Karakikes I, Mercola M. Serrano R, et al. Cell Stem Cell. 2023 Jan 5;30(1):86-95.e4. doi: 10.1016/j.stem.2022.12.002. Epub 2022 Dec 22. Cell Stem Cell. 2023. PMID: 36563695 Free PMC article.
Reengineering Ponatinib to Minimize Cardiovascular Toxicity.
Hnatiuk AP, Bruyneel AAN, Tailor D, Pandrala M, Dheeraj A, Li W, Serrano R, Feyen DAM, Vu MM, Amatya P, Gupta S, Nakauchi Y, Morgado I, Wiebking V, Liao R, Porteus MH, Majeti R, Malhotra SV, Mercola M. Hnatiuk AP, et al. Cancer Res. 2022 Aug 3;82(15):2777-2791. doi: 10.1158/0008-5472.CAN-21-3652. Cancer Res. 2022. PMID: 35763671 Free PMC article.
26 results