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Endothelial thrombomodulin downregulation caused by hypoxia contributes to severe infiltration and coagulopathy in COVID-19 patient lungs.
Won T, Wood MK, Hughes DM, Talor MV, Ma Z, Schneider J, Skinner JT, Asady B, Goerlich E, Halushka MK, Hays AG, Kim DH, Parikh CR, Rosenberg AZ, Coppens I, Johns RA, Gilotra NA, Hooper JE, Pekosz A, Čiháková D. Won T, et al. EBioMedicine. 2022 Jan;75:103812. doi: 10.1016/j.ebiom.2022.103812. Epub 2022 Jan 13. EBioMedicine. 2022. PMID: 35033854 Free PMC article.
Resistin family proteins in pulmonary diseases.
Lin Q, Johns RA. Lin Q, et al. Am J Physiol Lung Cell Mol Physiol. 2020 Sep 1;319(3):L422-L434. doi: 10.1152/ajplung.00040.2020. Epub 2020 Jun 17. Am J Physiol Lung Cell Mol Physiol. 2020. PMID: 32692581 Free PMC article. Review.
HIMF (Hypoxia-Induced Mitogenic Factor) Signaling Mediates the HMGB1 (High Mobility Group Box 1)-Dependent Endothelial and Smooth Muscle Cell Crosstalk in Pulmonary Hypertension.
Lin Q, Fan C, Gomez-Arroyo J, Van Raemdonck K, Meuchel LW, Skinner JT, Everett AD, Fang X, Macdonald AA, Yamaji-Kegan K, Johns RA. Lin Q, et al. Arterioscler Thromb Vasc Biol. 2019 Dec;39(12):2505-2519. doi: 10.1161/ATVBAHA.119.312907. Epub 2019 Oct 10. Arterioscler Thromb Vasc Biol. 2019. PMID: 31597444 Free PMC article.