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Year Number of Results
2009 1
2010 3
2011 2
2012 6
2013 7
2014 4
2020 0
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Page 1
Tau triage decisions mediated by the chaperone network.
Cook C, Petrucelli L. Cook C, et al. J Alzheimers Dis. 2013;33 Suppl 1:S145-51. doi: 10.3233/JAD-2012-129008. J Alzheimers Dis. 2013. PMID: 22596270 Review.
Progranulin: an emerging target for FTLD therapies.
Gass J, Prudencio M, Stetler C, Petrucelli L. Gass J, et al. Brain Res. 2012 Jun 26;1462:118-28. doi: 10.1016/j.brainres.2012.01.047. Epub 2012 Jan 28. Brain Res. 2012. PMID: 22338605 Free PMC article. Review.
Review: transactive response DNA-binding protein 43 (TDP-43): mechanisms of neurodegeneration.
Gendron TF, Josephs KA, Petrucelli L. Gendron TF, et al. Neuropathol Appl Neurobiol. 2010 Apr;36(2):97-112. doi: 10.1111/j.1365-2990.2010.01060.x. Epub 2010 Feb 19. Neuropathol Appl Neurobiol. 2010. PMID: 20202122 Free PMC article. Review.
Targeted manipulation of the sortilin-progranulin axis rescues progranulin haploinsufficiency.
Lee WC, Almeida S, Prudencio M, Caulfield TR, Zhang YJ, Tay WM, Bauer PO, Chew J, Sasaguri H, Jansen-West KR, Gendron TF, Stetler CT, Finch N, Mackenzie IR, Rademakers R, Gao FB, Petrucelli L. Lee WC, et al. Hum Mol Genet. 2014 Mar 15;23(6):1467-78. doi: 10.1093/hmg/ddt534. Epub 2013 Oct 26. Hum Mol Genet. 2014. PMID: 24163244 Free PMC article.
The dual functions of the extreme N-terminus of TDP-43 in regulating its biological activity and inclusion formation.
Zhang YJ, Caulfield T, Xu YF, Gendron TF, Hubbard J, Stetler C, Sasaguri H, Whitelaw EC, Cai S, Lee WC, Petrucelli L. Zhang YJ, et al. Hum Mol Genet. 2013 Aug 1;22(15):3112-22. doi: 10.1093/hmg/ddt166. Epub 2013 Apr 10. Hum Mol Genet. 2013. PMID: 23575225 Free PMC article.
Acetylation of the KXGS motifs in tau is a critical determinant in modulation of tau aggregation and clearance.
Cook C, Carlomagno Y, Gendron TF, Dunmore J, Scheffel K, Stetler C, Davis M, Dickson D, Jarpe M, DeTure M, Petrucelli L. Cook C, et al. Hum Mol Genet. 2014 Jan 1;23(1):104-16. doi: 10.1093/hmg/ddt402. Epub 2013 Aug 19. Hum Mol Genet. 2014. PMID: 23962722 Free PMC article.
Divergent phenotypes in mutant TDP-43 transgenic mice highlight potential confounds in TDP-43 transgenic modeling.
D'Alton S, Altshuler M, Cannon A, Dickson DW, Petrucelli L, Lewis J. D'Alton S, et al. PLoS One. 2014 Jan 22;9(1):e86513. doi: 10.1371/journal.pone.0086513. eCollection 2014. PLoS One. 2014. PMID: 24466128 Free PMC article.
Misregulation of human sortilin splicing leads to the generation of a nonfunctional progranulin receptor.
Prudencio M, Jansen-West KR, Lee WC, Gendron TF, Zhang YJ, Xu YF, Gass J, Stuani C, Stetler C, Rademakers R, Dickson DW, Buratti E, Petrucelli L. Prudencio M, et al. Proc Natl Acad Sci U S A. 2012 Dec 26;109(52):21510-5. doi: 10.1073/pnas.1211577110. Epub 2012 Dec 10. Proc Natl Acad Sci U S A. 2012. PMID: 23236149 Free PMC article.
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