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Page 1
Emerging Tim-3 functions in antimicrobial and tumor immunity.
Sakuishi K, Jayaraman P, Behar SM, Anderson AC, Kuchroo VK. Sakuishi K, et al. Trends Immunol. 2011 Aug;32(8):345-9. doi: 10.1016/j.it.2011.05.003. Epub 2011 Jun 21. Trends Immunol. 2011. PMID: 21697013 Free PMC article. Review.
The costimulatory role of TIM molecules.
Rodriguez-Manzanet R, DeKruyff R, Kuchroo VK, Umetsu DT. Rodriguez-Manzanet R, et al. Immunol Rev. 2009 May;229(1):259-70. doi: 10.1111/j.1600-065X.2009.00772.x. Immunol Rev. 2009. PMID: 19426227 Free PMC article. Review.
TIM-4 expressed on APCs induces T cell expansion and survival.
Rodriguez-Manzanet R, Meyers JH, Balasubramanian S, Slavik J, Kassam N, Dardalhon V, Greenfield EA, Anderson AC, Sobel RA, Hafler DA, Strom TB, Kuchroo VK. Rodriguez-Manzanet R, et al. J Immunol. 2008 Apr 1;180(7):4706-13. doi: 10.4049/jimmunol.180.7.4706. J Immunol. 2008. PMID: 18354194 Free PMC article.
TIM-1 and TIM-4 glycoproteins bind phosphatidylserine and mediate uptake of apoptotic cells.
Kobayashi N, Karisola P, Peña-Cruz V, Dorfman DM, Jinushi M, Umetsu SE, Butte MJ, Nagumo H, Chernova I, Zhu B, Sharpe AH, Ito S, Dranoff G, Kaplan GG, Casasnovas JM, Umetsu DT, Dekruyff RH, Freeman GJ. Kobayashi N, et al. Immunity. 2007 Dec;27(6):927-40. doi: 10.1016/j.immuni.2007.11.011. Immunity. 2007. PMID: 18082433 Free PMC article.