R01 NS046673/NS/NINDS NIH HHS/United States[Grant Number] - Search Results

Year	Number of Results
2005	2
2006	6
2007	5
2008	2
2009	7
2010	5
2011	4
2012	5
2013	4
2014	9
2015	3
2016	10
2017	4
2018	7
2019	2
2020	2
2024	0

1

Multi-omic comparison of Alzheimer's variants in human ESC-derived microglia reveals convergence at APOE.

Liu T, Zhu B, Liu Y, Zhang X, Yin J, Li X, Jiang L, Hodges AP, Rosenthal SB, Zhou L, Yancey J, McQuade A, Blurton-Jones M, Tanzi RE, Huang TY, Xu H. Liu T, et al. J Exp Med. 2020 Dec 7;217(12):e20200474. doi: 10.1084/jem.20200474. J Exp Med. 2020. PMID: 32941599 Free PMC article.

2

Soluble SORLA Enhances Neurite Outgrowth and Regeneration through Activation of the EGF Receptor/ERK Signaling Axis.

Stupack J, Xiong XP, Jiang LL, Zhang T, Zhou L, Campos A, Ranscht B, Mobley W, Pasquale EB, Xu H, Huang TY. Stupack J, et al. J Neurosci. 2020 Jul 29;40(31):5908-5921. doi: 10.1523/JNEUROSCI.0723-20.2020. Epub 2020 Jun 29. J Neurosci. 2020. PMID: 32601248 Free PMC article.

3

Membralin deficiency dysregulates astrocytic glutamate homeostasis leading to ALS-like impairment.

Jiang LL, Zhu B, Zhao Y, Li X, Liu T, Pina-Crespo J, Zhou L, Xu W, Rodriguez MJ, Yu H, Cleveland DW, Ravits J, Da Cruz S, Long T, Zhang D, Huang TY, Xu H. Jiang LL, et al. J Clin Invest. 2019 May 21;129(8):3103-3120. doi: 10.1172/JCI127695. J Clin Invest. 2019. PMID: 31112137 Free PMC article.

4

RPS23RG1 Is Required for Synaptic Integrity and Rescues Alzheimer's Disease-Associated Cognitive Deficits.

Zhao D, Meng J, Zhao Y, Huo Y, Liu Y, Zheng N, Zhang M, Gao Y, Chen Z, Sun H, Wang X, Jing C, Zhang T, Zhang X, Luo H, Wang X, Zhang J, Liu FR, Li Y, Bu G, Wen L, Huang TY, Xu H, Zhang YW. Zhao D, et al. Biol Psychiatry. 2019 Aug 1;86(3):171-184. doi: 10.1016/j.biopsych.2018.08.009. Epub 2018 Aug 25. Biol Psychiatry. 2019. PMID: 30292394 Free PMC article.

5

Arginine Methyltransferase PRMT8 Provides Cellular Stress Tolerance in Aging Motoneurons.

Simandi Z, Pajer K, Karolyi K, Sieler T, Jiang LL, Kolostyak Z, Sari Z, Fekecs Z, Pap A, Patsalos A, Contreras GA, Reho B, Papp Z, Guo X, Horvath A, Kiss G, Keresztessy Z, Vámosi G, Hickman J, Xu H, Dormann D, Hortobagyi T, Antal M, Nógrádi A, Nagy L. Simandi Z, et al. J Neurosci. 2018 Aug 29;38(35):7683-7700. doi: 10.1523/JNEUROSCI.3389-17.2018. Epub 2018 Jul 27. J Neurosci. 2018. PMID: 30054395 Free PMC article.

6

Neuron-Specific Menin Deletion Leads to Synaptic Dysfunction and Cognitive Impairment by Modulating p35 Expression.

Zhuang K, Huang C, Leng L, Zheng H, Gao Y, Chen G, Ji Z, Sun H, Hu Y, Wu D, Shi M, Li H, Zhao Y, Zhang Y, Xue M, Bu G, Huang TY, Xu H, Zhang J. Zhuang K, et al. Cell Rep. 2018 Jul 17;24(3):701-712. doi: 10.1016/j.celrep.2018.06.055. Cell Rep. 2018. PMID: 30021166 Free PMC article.

7

Inhibition of PKCδ reduces amyloid-β levels and reverses Alzheimer disease phenotypes.

Du Y, Zhao Y, Li C, Zheng Q, Tian J, Li Z, Huang TY, Zhang W, Xu H. Du Y, et al. J Exp Med. 2018 Jun 4;215(6):1665-1677. doi: 10.1084/jem.20171193. Epub 2018 May 8. J Exp Med. 2018. PMID: 29739836 Free PMC article.

8

The Retromer Complex and Sorting Nexins in Neurodegenerative Diseases.

Zhang H, Huang T, Hong Y, Yang W, Zhang X, Luo H, Xu H, Wang X. Zhang H, et al. Front Aging Neurosci. 2018 Mar 26;10:79. doi: 10.3389/fnagi.2018.00079. eCollection 2018. Front Aging Neurosci. 2018. PMID: 29632483 Free PMC article. Review.

9

Intracellular trafficking of TREM2 is regulated by presenilin 1.

Zhao Y, Li X, Huang T, Jiang LL, Tan Z, Zhang M, Cheng IH, Wang X, Bu G, Zhang YW, Wang Q, Xu H. Zhao Y, et al. Exp Mol Med. 2017 Dec 1;49(12):e405. doi: 10.1038/emm.2017.200. Exp Mol Med. 2017. PMID: 29611543 Free PMC article.

10

Elevated TREM2 Gene Dosage Reprograms Microglia Responsivity and Ameliorates Pathological Phenotypes in Alzheimer's Disease Models.

Lee CYD, Daggett A, Gu X, Jiang LL, Langfelder P, Li X, Wang N, Zhao Y, Park CS, Cooper Y, Ferando I, Mody I, Coppola G, Xu H, Yang XW. Lee CYD, et al. Neuron. 2018 Mar 7;97(5):1032-1048.e5. doi: 10.1016/j.neuron.2018.02.002. Neuron. 2018. PMID: 29518357 Free PMC article.

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