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Year Number of Results
2011 5
2012 7
2013 7
2014 8
2015 3
2017 2
2018 1
2020 0
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31 results
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Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway.
Sun L, Wu J, Du F, Chen X, Chen ZJ. Sun L, et al. Science. 2013 Feb 15;339(6121):786-91. doi: 10.1126/science.1232458. Epub 2012 Dec 20. Science. 2013. PMID: 23258413 Free PMC article.
Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA.
Wu J, Sun L, Chen X, Du F, Shi H, Chen C, Chen ZJ. Wu J, et al. Science. 2013 Feb 15;339(6121):826-30. doi: 10.1126/science.1229963. Epub 2012 Dec 20. Science. 2013. PMID: 23258412 Free PMC article.
Detection of Microbial Infections Through Innate Immune Sensing of Nucleic Acids.
Tan X, Sun L, Chen J, Chen ZJ. Tan X, et al. Annu Rev Microbiol. 2018 Sep 8;72:447-478. doi: 10.1146/annurev-micro-102215-095605. Annu Rev Microbiol. 2018. PMID: 30200854 Review.
A STING-activating nanovaccine for cancer immunotherapy.
Luo M, Wang H, Wang Z, Cai H, Lu Z, Li Y, Du M, Huang G, Wang C, Chen X, Porembka MR, Lea J, Frankel AE, Fu YX, Chen ZJ, Gao J. Luo M, et al. Nat Nanotechnol. 2017 Jul;12(7):648-654. doi: 10.1038/nnano.2017.52. Epub 2017 Apr 24. Nat Nanotechnol. 2017. PMID: 28436963 Free PMC article.
Cyclic GMP-AMP synthase is an innate immune sensor of HIV and other retroviruses.
Gao D, Wu J, Wu YT, Du F, Aroh C, Yan N, Sun L, Chen ZJ. Gao D, et al. Science. 2013 Aug 23;341(6148):903-6. doi: 10.1126/science.1240933. Epub 2013 Aug 8. Science. 2013. PMID: 23929945 Free PMC article.
Ubiquitination in signaling to and activation of IKK.
Chen ZJ. Chen ZJ. Immunol Rev. 2012 Mar;246(1):95-106. doi: 10.1111/j.1600-065X.2012.01108.x. Immunol Rev. 2012. PMID: 22435549 Free PMC article. Review.
MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response.
Hou F, Sun L, Zheng H, Skaug B, Jiang QX, Chen ZJ. Hou F, et al. Cell. 2011 Aug 5;146(3):448-61. doi: 10.1016/j.cell.2011.06.041. Epub 2011 Jul 21. Cell. 2011. PMID: 21782231 Free PMC article.
Innate immune sensing and signaling of cytosolic nucleic acids.
Wu J, Chen ZJ. Wu J, et al. Annu Rev Immunol. 2014;32:461-88. doi: 10.1146/annurev-immunol-032713-120156. Annu Rev Immunol. 2014. PMID: 24655297 Review.
Apoptotic caspases prevent the induction of type I interferons by mitochondrial DNA.
Rongvaux A, Jackson R, Harman CC, Li T, West AP, de Zoete MR, Wu Y, Yordy B, Lakhani SA, Kuan CY, Taniguchi T, Shadel GS, Chen ZJ, Iwasaki A, Flavell RA. Rongvaux A, et al. Cell. 2014 Dec 18;159(7):1563-77. doi: 10.1016/j.cell.2014.11.037. Cell. 2014. PMID: 25525875 Free PMC article.
STING specifies IRF3 phosphorylation by TBK1 in the cytosolic DNA signaling pathway.
Tanaka Y, Chen ZJ. Tanaka Y, et al. Sci Signal. 2012 Mar 6;5(214):ra20. doi: 10.1126/scisignal.2002521. Sci Signal. 2012. PMID: 22394562 Free PMC article.
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