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2013 | 1 |
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The negative cell cycle regulators, p27(Kip1), p18(Ink4c), and GSK-3, play critical role in maintaining quiescence of adult human pancreatic β-cells and restrict their ability to proliferate.
Islets. 2013 Jul-Aug;5(4):156-69. doi: 10.4161/isl.25605. Epub 2013 Jul 29.
Islets. 2013.
PMID: 23896637
Free PMC article.
GSK-3 inactivation or depletion promotes β-cell replication via down regulation of the CDK inhibitor, p27 (Kip1).
Stein J, Milewski WM, Hara M, Steiner DF, Dey A.
Stein J, et al.
Islets. 2011 Jan-Feb;3(1):21-34. doi: 10.4161/isl.3.1.14435. Epub 2011 Jan 1.
Islets. 2011.
PMID: 21278490
Free PMC article.
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