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Nucleosome switches.

Schwab DJ, Bruinsma RF, Rudnick J, Widom J. Schwab DJ, et al. Phys Rev Lett. 2008 Jun 6;100(22):228105. doi: 10.1103/PhysRevLett.100.228105. Epub 2008 Jun 6. Phys Rev Lett. 2008. PMID: 18643465 Free PMC article.

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Poly(dA:dT) tracts: major determinants of nucleosome organization.

Segal E, Widom J. Segal E, et al. Curr Opin Struct Biol. 2009 Feb;19(1):65-71. doi: 10.1016/j.sbi.2009.01.004. Epub 2009 Feb 7. Curr Opin Struct Biol. 2009. PMID: 19208466 Free PMC article. Review.

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From DNA sequence to transcriptional behaviour: a quantitative approach.

Segal E, Widom J. Segal E, et al. Nat Rev Genet. 2009 Jul;10(7):443-56. doi: 10.1038/nrg2591. Nat Rev Genet. 2009. PMID: 19506578 Free PMC article. Review.

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Biological consequences of tightly bent DNA: the other life of a macromolecular celebrity.

Garcia HG, Grayson P, Han L, Inamdar M, Kondev J, Nelson PC, Phillips R, Widom J, Wiggins PA. Garcia HG, et al. Biopolymers. 2007 Feb 5;85(2):115-30. doi: 10.1002/bip.20627. Biopolymers. 2007. PMID: 17103419 Free PMC article. Review.

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Dynamics of nucleosome invasion by DNA binding proteins.

Tims HS, Gurunathan K, Levitus M, Widom J. Tims HS, et al. J Mol Biol. 2011 Aug 12;411(2):430-48. doi: 10.1016/j.jmb.2011.05.044. Epub 2011 Jun 6. J Mol Biol. 2011. PMID: 21669206 Free PMC article.

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Spontaneous sharp bending of double-stranded DNA.

Cloutier TE, Widom J. Cloutier TE, et al. Mol Cell. 2004 May 7;14(3):355-62. doi: 10.1016/s1097-2765(04)00210-2. Mol Cell. 2004. PMID: 15125838 Free article.

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Dynamics and function of compact nucleosome arrays.

Poirier MG, Oh E, Tims HS, Widom J. Poirier MG, et al. Nat Struct Mol Biol. 2009 Sep;16(9):938-44. doi: 10.1038/nsmb.1650. Epub 2009 Aug 23. Nat Struct Mol Biol. 2009. PMID: 19701201 Free PMC article.

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The DNA-encoded nucleosome organization of a eukaryotic genome.

Kaplan N, Moore IK, Fondufe-Mittendorf Y, Gossett AJ, Tillo D, Field Y, LeProust EM, Hughes TR, Lieb JD, Widom J, Segal E. Kaplan N, et al. Nature. 2009 Mar 19;458(7236):362-6. doi: 10.1038/nature07667. Epub 2008 Dec 17. Nature. 2009. PMID: 19092803 Free PMC article.

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Structural constraints in collaborative competition of transcription factors against the nucleosome.

Moyle-Heyrman G, Tims HS, Widom J. Moyle-Heyrman G, et al. J Mol Biol. 2011 Sep 30;412(4):634-46. doi: 10.1016/j.jmb.2011.07.032. Epub 2011 Jul 29. J Mol Biol. 2011. PMID: 21821044 Free PMC article.

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Two-step mechanism for modifier of transcription 1 (Mot1) enzyme-catalyzed displacement of TATA-binding protein (TBP) from DNA.

Moyle-Heyrman G, Viswanathan R, Widom J, Auble DT. Moyle-Heyrman G, et al. J Biol Chem. 2012 Mar 16;287(12):9002-12. doi: 10.1074/jbc.M111.333484. Epub 2012 Feb 1. J Biol Chem. 2012. PMID: 22298788 Free PMC article.

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