RNA targeting and cleavage by the type III-Dv CRISPR effector complex.
Schwartz EA, Bravo JPK, Ahsan M, Macias LA, McCafferty CL, Dangerfield TL, Walker JN, Brodbelt JS, Palermo G, Fineran PC, Fagerlund RD, Taylor DW.
Schwartz EA, et al.
Nat Commun. 2024 Apr 18;15(1):3324. doi: 10.1038/s41467-024-47506-y.
Nat Commun. 2024.
PMID: 38637512
Here, we determine the structures of the Synechocystis type III-Dv complex, an apparent evolutionary intermediate from multi-protein to single-protein type III effectors(9,10), in pre- and post-cleavage states. The structures show how multi-subunit fusion proteins in the e …
Here, we determine the structures of the Synechocystis type III-Dv complex, an apparent evolutionary intermediate from multi-protein to sing …