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2018 28
2019 35
2020 15
2021 5
2022 1
2024 0

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72 results

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A qualitative study of the impact of coronavirus disease (COVID-19) on psychological and financial wellbeing and engagement in care among men who have sex with men living with HIV in Thailand.
Nitpolprasert C, Anand T, Phanuphak N, Reiss P, Ananworanich J, Peay HL. Nitpolprasert C, et al. HIV Med. 2022 Mar;23(3):227-236. doi: 10.1111/hiv.13190. Epub 2021 Oct 11. HIV Med. 2022. PMID: 34634181 Free PMC article.
OBJECTIVES: The coronavirus disease (COVID-19) pandemic is an unprecedented event with massive global health and socio-economic impacts on vulnerable populations, especially people living with HIV. ...
OBJECTIVES: The coronavirus disease (COVID-19) pandemic is an unprecedented event with massive global health and socio-economic impac …
Exercise intensity regulates cytokine and klotho responses in men.
Middelbeek RJW, Motiani P, Brandt N, Nigro P, Zheng J, Virtanen KA, Kalliokoski KK, Hannukainen JC, Goodyear LJ. Middelbeek RJW, et al. Nutr Diabetes. 2021 Jan 7;11(1):5. doi: 10.1038/s41387-020-00144-x. Nutr Diabetes. 2021. PMID: 33414377 Free PMC article. Clinical Trial.
Single-cell lineage analysis reveals extensive multimodal transcriptional control during directed beta-cell differentiation.
Weng C, Xi J, Li H, Cui J, Gu A, Lai S, Leskov K, Ke L, Jin F, Li Y. Weng C, et al. Nat Metab. 2020 Dec;2(12):1443-1458. doi: 10.1038/s42255-020-00314-2. Epub 2020 Nov 30. Nat Metab. 2020. PMID: 33257854 Free PMC article.
The in vitro differentiation of insulin-producing beta-like cells can model aspects of human pancreatic development. Here, we generate 95,308 single-cell transcriptomes and reconstruct a lineage tree of the entire differentiation process from human embryonic stem ce …
The in vitro differentiation of insulin-producing beta-like cells can model aspects of human pancreatic development. Here, we generat …
Distinct antibody responses to SARS-CoV-2 in children and adults across the COVID-19 clinical spectrum.
Weisberg SP, Connors TJ, Zhu Y, Baldwin MR, Lin WH, Wontakal S, Szabo PA, Wells SB, Dogra P, Gray J, Idzikowski E, Stelitano D, Bovier FT, Davis-Porada J, Matsumoto R, Poon MML, Chait M, Mathieu C, Horvat B, Decimo D, Hudson KE, Zotti FD, Bitan ZC, La Carpia F, Ferrara SA, Mace E, Milner J, Moscona A, Hod E, Porotto M, Farber DL. Weisberg SP, et al. Nat Immunol. 2021 Jan;22(1):25-31. doi: 10.1038/s41590-020-00826-9. Epub 2020 Nov 5. Nat Immunol. 2021. PMID: 33154590 Free PMC article.
AMP-activated protein kinase contributes to cisplatin-induced renal epithelial cell apoptosis and acute kidney injury.
Jin X, An C, Jiao B, Safirstein RL, Wang Y. Jin X, et al. Am J Physiol Renal Physiol. 2020 Dec 1;319(6):F1073-F1080. doi: 10.1152/ajprenal.00354.2020. Epub 2020 Oct 26. Am J Physiol Renal Physiol. 2020. PMID: 33103444 Free PMC article.
Cisplatin, a commonly used anticancer drug, has been shown to induce acute kidney injury, which limits its clinical use in cancer treatment. ...Furthermore, silencing AMPK expression by siRNA attenuated cisplatin-induced p53 phosphorylation, Bax induction, and caspase 3 ac …
Cisplatin, a commonly used anticancer drug, has been shown to induce acute kidney injury, which limits its clinical use in cancer tre …
MMP9 inhibition increases autophagic flux in chronic heart failure.
Nandi SS, Katsurada K, Sharma NM, Anderson DR, Mahata SK, Patel KP. Nandi SS, et al. Am J Physiol Heart Circ Physiol. 2020 Dec 1;319(6):H1414-H1437. doi: 10.1152/ajpheart.00032.2020. Epub 2020 Oct 16. Am J Physiol Heart Circ Physiol. 2020. PMID: 33064567 Free PMC article.
The novelty and highlights of this report are as follows: 1) MMP9 regulates cardiomyocyte and fibroblast autophagy, 2) MMP9 inhibition protects CHF after myocardial infarction (MI) via increased cardiac autophagic flux, 3) MMP9 inhibition increased cardiac autophagy via activatio …
The novelty and highlights of this report are as follows: 1) MMP9 regulates cardiomyocyte and fibroblast autophagy, 2) MMP9 inhibition prote …
Structural and functional characterization of engineered bifunctional fusion proteins of CD39 and CD73 ectonucleotidases.
Zhong EH, Ledderose C, De Andrade Mello P, Enjyoji K, Lunderberg JM, Junger W, Robson SC. Zhong EH, et al. Am J Physiol Cell Physiol. 2021 Jan 1;320(1):C15-C29. doi: 10.1152/ajpcell.00430.2020. Epub 2020 Oct 14. Am J Physiol Cell Physiol. 2021. PMID: 33052071 Free PMC article.
We have engineered bifunctional enzymes made up from ectodomains (ECDs) of CD39 and CD73 within a single polypeptide. Human alkaline phosphatase-ectodomain (ALP-ECD) and human acid phosphatase-ectodomain (HAP-ECD) fusion proteins were also generated, characterized, …
We have engineered bifunctional enzymes made up from ectodomains (ECDs) of CD39 and CD73 within a single polypeptide. Human alkaline …
Consensus transcriptional regulatory networks of coronavirus-infected human cells.
Ochsner SA, Pillich RT, McKenna NJ. Ochsner SA, et al. Sci Data. 2020 Sep 22;7(1):314. doi: 10.1038/s41597-020-00628-6. Sci Data. 2020. PMID: 32963239 Free PMC article.
Establishing consensus around the transcriptional interface between coronavirus (CoV) infection and human cellular signaling pathways can catalyze the development of novel anti-CoV therapeutics. Here, we used publicly archived transcriptomic datasets to compute consensus r …
Establishing consensus around the transcriptional interface between coronavirus (CoV) infection and human cellular signaling pathways …
72 results