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Obesity and insulin resistance
Kahn BB and Flier JS. J Clin Invest 2000 - Review. PMID 10953022 Free PMC article.
Protein kinase C isoforms epsilon, eta, delta and zeta in murine adipocytes: expression, subcellular localization and tissue-specific regulation in insulin-resistant states.
Frevert EU and Kahn BB. Biochem J 1996. PMID 8670164 Free PMC article.
Although isoform-specific changes in PKC expression have been reported for skeletal muscle and liver in insulin-resistant states, little is known about these isoforms in adipocytes. Therefore we studied (1) expression and subcellular localization of these isoforms in murine adipocytes, (2) translocation of specific isoforms to membranes in response to treatment with insulin and phorbol 12-myristate 13-acetate (PMA) and (3) regulation of expression in insulin-resistant states. ...
Although isoform-specific changes in PKC expression have been reported for skeletal muscle and liver in insulin-resistant states, lit …
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