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Year Number of Results
2009 1
2011 1
2012 1
2013 1
2015 2
2016 1
2020 0
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Page 1
Integrated genomics and proteomics define huntingtin CAG length-dependent networks in mice.
Langfelder P, Cantle JP, Chatzopoulou D, Wang N, Gao F, Al-Ramahi I, Lu XH, Ramos EM, El-Zein K, Zhao Y, Deverasetty S, Tebbe A, Schaab C, Lavery DJ, Howland D, Kwak S, Botas J, Aaronson JS, Rosinski J, Coppola G, Horvath S, Yang XW. Langfelder P, et al. Nat Neurosci. 2016 Apr;19(4):623-33. doi: 10.1038/nn.4256. Epub 2016 Feb 22. Nat Neurosci. 2016. PMID: 26900923 Free PMC article.
N17 Modifies mutant Huntingtin nuclear pathogenesis and severity of disease in HD BAC transgenic mice.
Gu X, Cantle JP, Greiner ER, Lee CY, Barth AM, Gao F, Park CS, Zhang Z, Sandoval-Miller S, Zhang RL, Diamond M, Mody I, Coppola G, Yang XW. Gu X, et al. Neuron. 2015 Feb 18;85(4):726-41. doi: 10.1016/j.neuron.2015.01.008. Epub 2015 Feb 5. Neuron. 2015. PMID: 25661181 Free PMC article.
Cortical efferents lacking mutant huntingtin improve striatal neuronal activity and behavior in a conditional mouse model of Huntington's disease.
Estrada-Sánchez AM, Burroughs CL, Cavaliere S, Barton SJ, Chen S, Yang XW, Rebec GV. Estrada-Sánchez AM, et al. J Neurosci. 2015 Mar 11;35(10):4440-51. doi: 10.1523/JNEUROSCI.2812-14.2015. J Neurosci. 2015. PMID: 25762686 Free PMC article.
Network organization of the huntingtin proteomic interactome in mammalian brain.
Shirasaki DI, Greiner ER, Al-Ramahi I, Gray M, Boontheung P, Geschwind DH, Botas J, Coppola G, Horvath S, Loo JA, Yang XW. Shirasaki DI, et al. Neuron. 2012 Jul 12;75(1):41-57. doi: 10.1016/j.neuron.2012.05.024. Neuron. 2012. PMID: 22794259 Free PMC article.
An antisense CAG repeat transcript at JPH3 locus mediates expanded polyglutamine protein toxicity in Huntington's disease-like 2 mice.
Wilburn B, Rudnicki DD, Zhao J, Weitz TM, Cheng Y, Gu X, Greiner E, Park CS, Wang N, Sopher BL, La Spada AR, Osmand A, Margolis RL, Sun YE, Yang XW. Wilburn B, et al. Neuron. 2011 May 12;70(3):427-40. doi: 10.1016/j.neuron.2011.03.021. Neuron. 2011. PMID: 21555070 Free PMC article.
Serines 13 and 16 are critical determinants of full-length human mutant huntingtin induced disease pathogenesis in HD mice.
Gu X, Greiner ER, Mishra R, Kodali R, Osmand A, Finkbeiner S, Steffan JS, Thompson LM, Wetzel R, Yang XW. Gu X, et al. Neuron. 2009 Dec 24;64(6):828-40. doi: 10.1016/j.neuron.2009.11.020. Neuron. 2009. PMID: 20064390 Free PMC article.