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Altered temporal sequence of transcriptional regulators in the generation of human cerebellar granule cells.
Elife. 2021 Nov 29;10:e67074. doi: 10.7554/eLife.67074.
Elife. 2021.
PMID: 34842137
Free PMC article.
Novel genetic features of human and mouse Purkinje cell differentiation defined by comparative transcriptomics.
Buchholz DE, Carroll TS, Kocabas A, Zhu X, Behesti H, Faust PL, Stalbow L, Fang Y, Hatten ME.
Buchholz DE, et al.
Proc Natl Acad Sci U S A. 2020 Jun 30;117(26):15085-15095. doi: 10.1073/pnas.2000102117. Epub 2020 Jun 16.
Proc Natl Acad Sci U S A. 2020.
PMID: 32546527
Free PMC article.
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Murine astrotactins 1 and 2 have a similar membrane topology and mature via endoproteolytic cleavage catalyzed by a signal peptidase.
Lara P, Tellgren-Roth Å, Behesti H, Horn Z, Schiller N, Enquist K, Cammenberg M, Liljenström A, Hatten ME, von Heijne G, Nilsson I.
Lara P, et al.
J Biol Chem. 2019 Mar 22;294(12):4538-4545. doi: 10.1074/jbc.RA118.007093. Epub 2019 Jan 29.
J Biol Chem. 2019.
PMID: 30696770
Free PMC article.
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N-cadherin provides a cis and trans ligand for astrotactin that functions in glial-guided neuronal migration.
Horn Z, Behesti H, Hatten ME.
Horn Z, et al.
Proc Natl Acad Sci U S A. 2018 Oct 16;115(42):10556-10563. doi: 10.1073/pnas.1811100115. Epub 2018 Sep 27.
Proc Natl Acad Sci U S A. 2018.
PMID: 30262652
Free PMC article.
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Purkinje cells derived from TSC patients display hypoexcitability and synaptic deficits associated with reduced FMRP levels and reversed by rapamycin.
Sundberg M, Tochitsky I, Buchholz DE, Winden K, Kujala V, Kapur K, Cataltepe D, Turner D, Han MJ, Woolf CJ, Hatten ME, Sahin M.
Sundberg M, et al.
Mol Psychiatry. 2018 Nov;23(11):2167-2183. doi: 10.1038/s41380-018-0018-4. Epub 2018 Feb 15.
Mol Psychiatry. 2018.
PMID: 29449635
Free PMC article.
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Role of Tet1/3 Genes and Chromatin Remodeling Genes in Cerebellar Circuit Formation.
Zhu X, Girardo D, Govek EE, John K, Mellén M, Tamayo P, Mesirov JP, Hatten ME.
Zhu X, et al.
Neuron. 2016 Jan 6;89(1):100-12. doi: 10.1016/j.neuron.2015.11.030. Epub 2015 Dec 17.
Neuron. 2016.
PMID: 26711116
Free PMC article.
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