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Acute, low-dose methamphetamine administration improves attention/information processing speed and working memory in methamphetamine-dependent individuals displaying poorer cognitive performance at baseline.
Mahoney JJ 3rd, Jackson BJ, Kalechstein AD, De La Garza R 2nd, Newton TF. Mahoney JJ 3rd, et al. Prog Neuropsychopharmacol Biol Psychiatry. 2011 Mar 30;35(2):459-65. doi: 10.1016/j.pnpbp.2010.11.034. Epub 2010 Nov 29. Prog Neuropsychopharmacol Biol Psychiatry. 2011. PMID: 21122811 Free PMC article. Clinical Trial.
The acetylcholinesterase inhibitor rivastigmine does not alter total choices for methamphetamine, but may reduce positive subjective effects, in a laboratory model of intravenous self-administration in human volunteers.
De La Garza R 2nd, Mahoney JJ 3rd, Culbertson C, Shoptaw S, Newton TF. De La Garza R 2nd, et al. Pharmacol Biochem Behav. 2008 Apr;89(2):200-8. doi: 10.1016/j.pbb.2007.12.010. Epub 2008 Jan 22. Pharmacol Biochem Behav. 2008. PMID: 18207225 Free PMC article. Clinical Trial.