R35 GM126982/GM/NIGMS NIH HHS/United States[Grant Number] - Search Results

Year	Number of Results
2018	2
2019	8
2020	10
2021	8
2022	6

1

Ribonucleotide Reductases: Structure, Chemistry, and Metabolism Suggest New Therapeutic Targets.

Greene BL, Kang G, Cui C, Bennati M, Nocera DG, Drennan CL, Stubbe J. Greene BL, et al. Annu Rev Biochem. 2020 Jun 20;89:45-75. doi: 10.1146/annurev-biochem-013118-111843. Annu Rev Biochem. 2020. PMID: 32569524 Free PMC article. Review.

2

Structural basis for non-radical catalysis by TsrM, a radical SAM methylase.

Knox HL, Chen PY, Blaszczyk AJ, Mukherjee A, Grove TL, Schwalm EL, Wang B, Drennan CL, Booker SJ. Knox HL, et al. Nat Chem Biol. 2021 Apr;17(4):485-491. doi: 10.1038/s41589-020-00717-y. Epub 2021 Jan 18. Nat Chem Biol. 2021. PMID: 33462497 Free PMC article.

3

Crystal Structure of the [4Fe-4S] Cluster-Containing Adenosine-5'-phosphosulfate Reductase from Mycobacterium tuberculosis.

Feliciano PR, Carroll KS, Drennan CL. Feliciano PR, et al. ACS Omega. 2021 May 17;6(21):13756-13765. doi: 10.1021/acsomega.1c01043. eCollection 2021 Jun 1. ACS Omega. 2021. PMID: 34095667 Free PMC article.

4

Rescuing activity of oxygen-damaged pyruvate formate-lyase by a spare part protein.

Andorfer MC, Backman LRF, Li PL, Ulrich EC, Drennan CL. Andorfer MC, et al. J Biol Chem. 2021 Dec;297(6):101423. doi: 10.1016/j.jbc.2021.101423. Epub 2021 Nov 18. J Biol Chem. 2021. PMID: 34801558 Free PMC article.

5

Molecular basis of C-S bond cleavage in the glycyl radical enzyme isethionate sulfite-lyase.

Dawson CD, Irwin SM, Backman LRF, Le C, Wang JX, Vennelakanti V, Yang Z, Kulik HJ, Drennan CL, Balskus EP. Dawson CD, et al. Cell Chem Biol. 2021 Sep 16;28(9):1333-1346.e7. doi: 10.1016/j.chembiol.2021.03.001. Epub 2021 Mar 26. Cell Chem Biol. 2021. PMID: 33773110 Free PMC article.

6

Biochemical and crystallographic investigations into isonitrile formation by a nonheme iron-dependent oxidase/decarboxylase.

Jonnalagadda R, Del Rio Flores A, Cai W, Mehmood R, Narayanamoorthy M, Ren C, Zaragoza JPT, Kulik HJ, Zhang W, Drennan CL. Jonnalagadda R, et al. J Biol Chem. 2021 Jan-Jun;296:100231. doi: 10.1074/jbc.RA120.015932. Epub 2021 Jan 7. J Biol Chem. 2021. PMID: 33361191 Free PMC article.

7

Gated Proton Release during Radical Transfer at the Subunit Interface of Ribonucleotide Reductase.

Cui C, Greene BL, Kang G, Drennan CL, Stubbe J, Nocera DG. Cui C, et al. J Am Chem Soc. 2021 Jan 13;143(1):176-183. doi: 10.1021/jacs.0c07879. Epub 2020 Dec 23. J Am Chem Soc. 2021. PMID: 33353307 Free PMC article.

8

Negative-Stain Electron Microscopy Reveals Dramatic Structural Rearrangements in Ni-Fe-S-Dependent Carbon Monoxide Dehydrogenase/Acetyl-CoA Synthase.

Cohen SE, Brignole EJ, Wittenborn EC, Can M, Thompson S, Ragsdale SW, Drennan CL. Cohen SE, et al. Structure. 2021 Jan 7;29(1):43-49.e3. doi: 10.1016/j.str.2020.08.011. Epub 2020 Sep 15. Structure. 2021. PMID: 32937101 Free PMC article.

9

A Stable Ferryl Porphyrin at the Active Site of Y463M BthA.

Rizzolo K, Weitz AC, Cohen SE, Drennan CL, Hendrich MP, Elliott SJ. Rizzolo K, et al. J Am Chem Soc. 2020 Jul 15;142(28):11978-11982. doi: 10.1021/jacs.0c04023. Epub 2020 Jul 1. J Am Chem Soc. 2020. PMID: 32564595 Free PMC article.

10

Structural insight into metallocofactor maturation in carbon monoxide dehydrogenase.

Wittenborn EC, Cohen SE, Merrouch M, Léger C, Fourmond V, Dementin S, Drennan CL. Wittenborn EC, et al. J Biol Chem. 2019 Aug 30;294(35):13017-13026. doi: 10.1074/jbc.RA119.009610. Epub 2019 Jul 11. J Biol Chem. 2019. PMID: 31296570 Free PMC article.

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