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Kidney cancer biomarkers and targets for therapeutics: survivin (BIRC5), XIAP, MCL-1, HIF1α, HIF2α, NRF2, MDM2, MDM4, p53, KRAS and AKT in renal cell carcinoma.
J Exp Clin Cancer Res. 2021 Aug 12;40(1):254. doi: 10.1186/s13046-021-02026-1.
J Exp Clin Cancer Res. 2021.
PMID: 34384473
Free PMC article.
Review.
Cancer therapeutics using survivin BIRC5 as a target: what can we do after over two decades of study?
Li F, Aljahdali I, Ling X.
Li F, et al.
J Exp Clin Cancer Res. 2019 Aug 22;38(1):368. doi: 10.1186/s13046-019-1362-1.
J Exp Clin Cancer Res. 2019.
PMID: 31439015
Free PMC article.
Review.
Item in Clipboard
Structure-Activity Relationship of FL118 Platform Position 7 Versus Position 9-Derived Compounds and Their Mechanism of Action and Antitumor Activity.
Wang W, Ling X, Wang R, Xiong H, Hu L, Yang Z, Wang H, Zhang Y, Wu W, Singh PK, Wang J, Li F, Li Q.
Wang W, et al.
J Med Chem. 2023 Dec 28;66(24):16888-16916. doi: 10.1021/acs.jmedchem.3c01589. Epub 2023 Dec 15.
J Med Chem. 2023.
PMID: 38100041
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An ABCG2 non-substrate anticancer agent FL118 targets drug-resistant cancer stem-like cells and overcomes treatment resistance of human pancreatic cancer.
Ling X, Wu W, Fan C, Xu C, Liao J, Rich LJ, Huang RY, Repasky EA, Wang X, Li F.
Ling X, et al.
J Exp Clin Cancer Res. 2018 Oct 3;37(1):240. doi: 10.1186/s13046-018-0899-8.
J Exp Clin Cancer Res. 2018.
PMID: 30285798
Free PMC article.
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