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Page 1
Aptamers and the next generation of diagnostic reagents.
Thiviyanathan V, Gorenstein DG. Thiviyanathan V, et al. Proteomics Clin Appl. 2012 Dec;6(11-12):563-73. doi: 10.1002/prca.201200042. Proteomics Clin Appl. 2012. PMID: 23090891 Free PMC article. Review.
Strategies for the discovery of therapeutic aptamers.
Yang X, Li N, Gorenstein DG. Yang X, et al. Expert Opin Drug Discov. 2011 Jan;6(1):75-87. doi: 10.1517/17460441.2011.537321. Expert Opin Drug Discov. 2011. PMID: 21359096 Free PMC article.
Thioaptamer conjugated liposomes for tumor vasculature targeting.
Mann AP, Bhavane RC, Somasunderam A, Liz Montalvo-Ortiz B, Ghaghada KB, Volk D, Nieves-Alicea R, Suh KS, Ferrari M, Annapragada A, Gorenstein DG, Tanaka T. Mann AP, et al. Oncotarget. 2011 Apr;2(4):298-304. doi: 10.18632/oncotarget.261. Oncotarget. 2011. PMID: 21666286 Free PMC article.
A miR-192-EGR1-HOXB9 regulatory network controls the angiogenic switch in cancer.
Wu SY, Rupaimoole R, Shen F, Pradeep S, Pecot CV, Ivan C, Nagaraja AS, Gharpure KM, Pham E, Hatakeyama H, McGuire MH, Haemmerle M, Vidal-Anaya V, Olsen C, Rodriguez-Aguayo C, Filant J, Ehsanipour EA, Herbrich SM, Maiti SN, Huang L, Kim JH, Zhang X, Han HD, Armaiz-Pena GN, Seviour EG, Tucker S, Zhang M, Yang D, Cooper LJ, Ali-Fehmi R, Bar-Eli M, Lee JS, Ram PT, Baggerly KA, Lopez-Berestein G, Hung MC, Sood AK. Wu SY, et al. Nat Commun. 2016 Apr 4;7:11169. doi: 10.1038/ncomms11169. Nat Commun. 2016. PMID: 27041221 Free PMC article.
2'-OMe-phosphorodithioate-modified siRNAs show increased loading into the RISC complex and enhanced anti-tumour activity.
Wu SY, Yang X, Gharpure KM, Hatakeyama H, Egli M, McGuire MH, Nagaraja AS, Miyake TM, Rupaimoole R, Pecot CV, Taylor M, Pradeep S, Sierant M, Rodriguez-Aguayo C, Choi HJ, Previs RA, Armaiz-Pena GN, Huang L, Martinez C, Hassell T, Ivan C, Sehgal V, Singhania R, Han HD, Su C, Kim JH, Dalton HJ, Kovvali C, Keyomarsi K, McMillan NA, Overwijk WW, Liu J, Lee JS, Baggerly KA, Lopez-Berestein G, Ram PT, Nawrot B, Sood AK. Wu SY, et al. Nat Commun. 2014 Mar 12;5:3459. doi: 10.1038/ncomms4459. Nat Commun. 2014. PMID: 24619206 Free PMC article.