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GLYX-13, a NMDA receptor glycine-site functional partial agonist, induces antidepressant-like effects without ketamine-like side effects.
Neuropsychopharmacology. 2013 Apr;38(5):729-42. doi: 10.1038/npp.2012.246. Epub 2012 Dec 5.
Neuropsychopharmacology. 2013.
PMID: 23303054
Free PMC article.
The N-methyl-D-aspartate receptor modulator GLYX-13 enhances learning and memory, in young adult and learning impaired aging rats.
Burgdorf J, Zhang XL, Weiss C, Matthews E, Disterhoft JF, Stanton PK, Moskal JR.
Burgdorf J, et al.
Neurobiol Aging. 2011 Apr;32(4):698-706. doi: 10.1016/j.neurobiolaging.2009.04.012. Epub 2009 May 14.
Neurobiol Aging. 2011.
PMID: 19446371
Free PMC article.
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A NMDA receptor glycine site partial agonist, GLYX-13, simultaneously enhances LTP and reduces LTD at Schaffer collateral-CA1 synapses in hippocampus.
Zhang XL, Sullivan JA, Moskal JR, Stanton PK.
Zhang XL, et al.
Neuropharmacology. 2008 Dec;55(7):1238-50. doi: 10.1016/j.neuropharm.2008.08.018. Epub 2008 Aug 29.
Neuropharmacology. 2008.
PMID: 18796308
Free PMC article.
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