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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2007 1
2008 6
2009 6
2010 3
2011 5
2012 4
2013 8
2014 9
2015 3
2016 2
2017 1
2018 1
2019 3
2020 1
2021 1
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48 results
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Page 1
DNA sensing by the cGAS-STING pathway in health and disease.
Motwani M, Pesiridis S, Fitzgerald KA. Motwani M, et al. Nat Rev Genet. 2019 Nov;20(11):657-674. doi: 10.1038/s41576-019-0151-1. Epub 2019 Jul 29. Nat Rev Genet. 2019. PMID: 31358977 Review.
Gasdermins and their role in immunity and inflammation.
Orning P, Lien E, Fitzgerald KA. Orning P, et al. J Exp Med. 2019 Nov 4;216(11):2453-2465. doi: 10.1084/jem.20190545. Epub 2019 Sep 23. J Exp Med. 2019. PMID: 31548300 Free PMC article. Review.
Pathogen blockade of TAK1 triggers caspase-8-dependent cleavage of gasdermin D and cell death.
Orning P, Weng D, Starheim K, Ratner D, Best Z, Lee B, Brooks A, Xia S, Wu H, Kelliher MA, Berger SB, Gough PJ, Bertin J, Proulx MM, Goguen JD, Kayagaki N, Fitzgerald KA, Lien E. Orning P, et al. Science. 2018 Nov 30;362(6418):1064-1069. doi: 10.1126/science.aau2818. Epub 2018 Oct 25. Science. 2018. PMID: 30361383 Free PMC article.
STING-dependent cytosolic DNA sensing mediates innate immune recognition of immunogenic tumors.
Woo SR, Fuertes MB, Corrales L, Spranger S, Furdyna MJ, Leung MY, Duggan R, Wang Y, Barber GN, Fitzgerald KA, Alegre ML, Gajewski TF. Woo SR, et al. Immunity. 2014 Nov 20;41(5):830-42. doi: 10.1016/j.immuni.2014.10.017. Epub 2014 Nov 5. Immunity. 2014. PMID: 25517615 Free PMC article.
IFI16 is an innate immune sensor for intracellular DNA.
Unterholzner L, Keating SE, Baran M, Horan KA, Jensen SB, Sharma S, Sirois CM, Jin T, Latz E, Xiao TS, Fitzgerald KA, Paludan SR, Bowie AG. Unterholzner L, et al. Nat Immunol. 2010 Nov;11(11):997-1004. doi: 10.1038/ni.1932. Epub 2010 Oct 3. Nat Immunol. 2010. PMID: 20890285 Free PMC article.
A Long Noncoding RNA lincRNA-EPS Acts as a Transcriptional Brake to Restrain Inflammation.
Atianand MK, Hu W, Satpathy AT, Shen Y, Ricci EP, Alvarez-Dominguez JR, Bhatta A, Schattgen SA, McGowan JD, Blin J, Braun JE, Gandhi P, Moore MJ, Chang HY, Lodish HF, Caffrey DR, Fitzgerald KA. Atianand MK, et al. Cell. 2016 Jun 16;165(7):1672-1685. doi: 10.1016/j.cell.2016.05.075. Cell. 2016. PMID: 27315481 Free PMC article.
A long noncoding RNA mediates both activation and repression of immune response genes.
Carpenter S, Aiello D, Atianand MK, Ricci EP, Gandhi P, Hall LL, Byron M, Monks B, Henry-Bezy M, Lawrence JB, O'Neill LA, Moore MJ, Caffrey DR, Fitzgerald KA. Carpenter S, et al. Science. 2013 Aug 16;341(6147):789-92. doi: 10.1126/science.1240925. Epub 2013 Aug 1. Science. 2013. PMID: 23907535 Free PMC article.
A Mitochondrial Micropeptide Is Required for Activation of the Nlrp3 Inflammasome.
Bhatta A, Atianand M, Jiang Z, Crabtree J, Blin J, Fitzgerald KA. Bhatta A, et al. J Immunol. 2020 Jan 15;204(2):428-437. doi: 10.4049/jimmunol.1900791. Epub 2019 Dec 13. J Immunol. 2020. PMID: 31836654 Free PMC article.
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome.
Nakahira K, Haspel JA, Rathinam VA, Lee SJ, Dolinay T, Lam HC, Englert JA, Rabinovitch M, Cernadas M, Kim HP, Fitzgerald KA, Ryter SW, Choi AM. Nakahira K, et al. Nat Immunol. 2011 Mar;12(3):222-30. doi: 10.1038/ni.1980. Epub 2010 Dec 12. Nat Immunol. 2011. PMID: 21151103 Free PMC article.
Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression.
Bauernfeind FG, Horvath G, Stutz A, Alnemri ES, MacDonald K, Speert D, Fernandes-Alnemri T, Wu J, Monks BG, Fitzgerald KA, Hornung V, Latz E. Bauernfeind FG, et al. J Immunol. 2009 Jul 15;183(2):787-91. doi: 10.4049/jimmunol.0901363. Epub 2009 Jul 1. J Immunol. 2009. PMID: 19570822 Free PMC article.
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