R56 DK046577/DK/NIDDK NIH HHS/United States[Grant Number] - Search Results

Year	Number of Results
2006	1
2008	5
2009	5
2010	7
2011	6
2012	6
2013	5
2014	3
2016	2
2022	0

1

Minireview: Signal bias, allosterism, and polymorphic variation at the GLP-1R: implications for drug discovery.

Koole C, Savage EE, Christopoulos A, Miller LJ, Sexton PM, Wootten D. Koole C, et al. Mol Endocrinol. 2013 Aug;27(8):1234-44. doi: 10.1210/me.2013-1116. Epub 2013 Jul 17. Mol Endocrinol. 2013. PMID: 23864649 Free PMC article. Review.

2

Ligand binding and activation of the secretin receptor, a prototypic family B G protein-coupled receptor.

Miller LJ, Dong M, Harikumar KG. Miller LJ, et al. Br J Pharmacol. 2012 May;166(1):18-26. doi: 10.1111/j.1476-5381.2011.01463.x. Br J Pharmacol. 2012. PMID: 21542831 Free PMC article. Review.

3

Structural and functional insights into the juxtamembranous amino-terminal tail and extracellular loop regions of class B GPCRs.

Dong M, Koole C, Wootten D, Sexton PM, Miller LJ. Dong M, et al. Br J Pharmacol. 2014 Mar;171(5):1085-101. doi: 10.1111/bph.12293. Br J Pharmacol. 2014. PMID: 23889342 Free PMC article. Review.

4

The class B G-protein-coupled GLP-1 receptor: an important target for the treatment of type-2 diabetes mellitus.

Miller LJ, Sexton PM, Dong M, Harikumar KG. Miller LJ, et al. Int J Obes Suppl. 2014 Jul;4(Suppl 1):S9-S13. doi: 10.1038/ijosup.2014.4. Epub 2014 Jul 8. Int J Obes Suppl. 2014. PMID: 27152167 Free PMC article. Review.

5

Alternative splicing of pre-mRNA in cancer: focus on G protein-coupled peptide hormone receptors.

Körner M, Miller LJ. Körner M, et al. Am J Pathol. 2009 Aug;175(2):461-72. doi: 10.2353/ajpath.2009.081135. Epub 2009 Jul 2. Am J Pathol. 2009. PMID: 19574427 Free PMC article. Review.

6

Seven transmembrane receptors as shapeshifting proteins: the impact of allosteric modulation and functional selectivity on new drug discovery.

Kenakin T, Miller LJ. Kenakin T, et al. Pharmacol Rev. 2010 Jun;62(2):265-304. doi: 10.1124/pr.108.000992. Epub 2010 Apr 14. Pharmacol Rev. 2010. PMID: 20392808 Free PMC article. Review.

7

Structure and function of Norrin in assembly and activation of a Frizzled 4-Lrp5/6 complex.

Ke J, Harikumar KG, Erice C, Chen C, Gu X, Wang L, Parker N, Cheng Z, Xu W, Williams BO, Melcher K, Miller LJ, Xu HE. Ke J, et al. Genes Dev. 2013 Nov 1;27(21):2305-19. doi: 10.1101/gad.228544.113. Genes Dev. 2013. PMID: 24186977 Free PMC article.

8

Importance of each residue within secretin for receptor binding and biological activity.

Dong M, Le A, Te JA, Pinon DI, Bordner AJ, Miller LJ. Dong M, et al. Biochemistry. 2011 Apr 12;50(14):2983-93. doi: 10.1021/bi200133u. Epub 2011 Mar 21. Biochemistry. 2011. PMID: 21388146 Free PMC article.

9

Receptor activity-modifying protein-dependent impairment of calcitonin receptor splice variant Δ(1-47)hCT((a)) function.

Qi T, Dong M, Watkins HA, Wootten D, Miller LJ, Hay DL. Qi T, et al. Br J Pharmacol. 2013 Feb;168(3):644-57. doi: 10.1111/j.1476-5381.2012.02197.x. Br J Pharmacol. 2013. PMID: 22946511 Free PMC article.

10

Characterization of alternative spliceoforms and the RNA splicing machinery in pancreatic cancer.

Carrigan PE, Bingham JL, Srinvasan S, Brentnall TA, Miller LJ. Carrigan PE, et al. Pancreas. 2011 Mar;40(2):281-8. doi: 10.1097/MPA.0b013e31820128d2. Pancreas. 2011. PMID: 21178653 Free PMC article.

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